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syn117 hydrochloride

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  • Inhibitors & Agonists
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Nepicastat hydrochloride
Nepicastat HCl, RS-25560-197 hydrochloride, SYN-117 hydrochloride, Nepicastat (SYN-117) HCl
T6604170151-24-3
Nepicastat hydrochloride (RS-25560-197 hydrochloride) is an effective and specific inhibitor, which is used for bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, respectively.The affinity of Nepicastat for twelve other enzymes and thirteen neurotransmitter receptors is negligible.
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Nepicastat hydrochloride monohydrate
T70209177645-08-8
Nepicastat hydrochloride monohydrate is an inhibitor of dopamine beta-hydroxylase, an enzyme that catalyzes the conversion of dopamine to norepinephrine.
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1-2 weeks
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Nepicastat
T60633173997-05-2
Nepicastat (SYN117) is a selective, potent, and orally active dopamine-beta-hydroxylase inhibitor capable of crossing the blood-brain barrier (BBB), producing concentration-dependent inhibition of bovine and human dopamine-beta-hydroxylase with IC50s of 8.5 nM and 9 nM [1] [2] [3].
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1-2 weeks
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(R)-Nepicastat HCl
RS-25560-198 HCl
T6356195881-94-8
(R)-Nepicastat HCl (RS-25560-198 HCl), the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.
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6-8 weeks
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