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By Target- c-Fms
- CSF-1R(1)
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Results for "
sotuletinib
" in TargetMol Product Catalog- Inhibitors & Agonists2
sotuletinib
BLZ945
T6119953769-46-5
Sotuletinib (BLZ945) is an orally active, effective and specific CSF-1R inhibitor (IC50: 1 nM), >1000-fold selective against its closest receptor tyrosine kinase homologs.
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Sotuletinib dihydrochloride
BLZ945 dihydrochloride
T786032222138-40-9
Sotuletinib (BLZ945) dihydrochloride is an orally administered, blood-brain barrier-permeable CSF1-R inhibitor with an IC50 of 1 nM, promoting apoptosis in tumor cells and significantly restricting tumor growth in murine models, thereby proving useful in cancer and amyotrophic lateral sclerosis (ALS) studies [1].
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