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By Target- Melanocortin Receptor
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Results for "
shu-9119
" in TargetMol Product Catalog- Inhibitors & Agonists3
- Peptide Products3
SHU 9119 acetate
SHU 9119 acetate (168482-23-3 free base)
T16879L
SHU 9119 acetate is a well-known antagonist of human melanocortin 3 and 4 (hMC3R, hMC4R) receptors and a partial hMC5R agonist. The IC50 values of human MC3R, MC4R and MC5R is 0.23, 0.06, and 0.09 nM respectively.
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PG-931 TFA
T75847
PG-931 TFA, a potent and selective agonist of the melanocortin 4 (MC4) receptor (IC50=0.58 nM) compared to the hMC3R (IC50=55 nM) and hMC5R (IC50=2.4 nM), is an analog of SHU 9119. This compound has demonstrated efficacy in reversing hemorrhagic shock and preventing multiple organ damage in vivo [2].
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