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Results for "
sf3b
" in TargetMol Product Catalog- Inhibitors & Agonists3
- PROTAC Products1
- Recombinant Protein1
- Antibody Products4
Thailanstatin A 
T388891426953-21-0
Thailanstatin A is an ultra-potent inhibitor of eukaryotic RNA splicing (IC50 = 650 nM). It inhibits multiple cancer cell lines via non-covalent binding to the SF3b subunit of the U2 snRNA subcomplex of the spliceosome, displaying low-nM to sub-nM IC50s. Thailanstatin A, as a payload for ADCs, is conjugated to the lysines on trastuzumab, yielding linker-less ADC.
- $187
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