sesamin

Sesamin is a selective delta 5 desaturase inhibitor in the biosynthesis of polyunsaturated fatty acids and is a lignan abundantly present in sesame oil. It has potent neuroprotective effects against cerebral ischemia.

(-)-Sesamin is a natural product with neuroprotective effects. It protects against 6-OHDA-induced neurotoxicity by activating ERK1/2-BadSer112 and inhibiting ERK-p38MAPK-JNK1/2-caspase-3 pathways, making it useful for Parkinson's disease research.

(-)-Asarinin (Eleutheroside B4) shows antibacterial activity.

Sesamin (Standard) is a reference standard for research and analysis in studies involving Sesamin. Sesamin is a selective delta 5 desaturase inhibitor in the biosynthesis of polyunsaturated fatty acids and is a lignan abundantly present in sesame oil. It has potent neuroprotective effects against cerebral ischemia.

(-)-Sesamin 2,2'-diol is a natural product for research related to life sciences. The catalog number is TN6139 and the CAS number is 1152441-87-6.

Sesaminol is an orally active activator of the Nrf2-ARE signaling pathway, promoting the nuclear translocation of Nrf2 and boosting the expression of NQO1 to enhance cellular defense against oxidative stress. It inhibits 6-OHDA-induced ROS production and apoptosis in SH-SY5Y cells. Sesaminol also provides neuroprotective effects against Rotenone-induced Parkinson's disease.

Dihydrosesamin is a natural product of Chamaecyparis, Cupressaceae. The catalog number is TN3865 and the CAS number is 83708-70-7. Dihydrosesamin can be used as a reference standard.

L-asarinin ((-)-Episesamin) reduces peripheral blood concentration of IL-12 and inhibits the expression of CXCR3 and TLR4, which means Asarinin may have a role on the TLR4 pathway and produce prolongation of allograft heart survival.

1. Sesamolin and Sesamin has neuroprotective effect. 2. Sesamolin protects microglia against H2O2-induced cell injury, by inhibiting of p38 MAPK and caspase-3 activation and ROS production. 3. Sesamolin and Sesamin can significantly attenuate the excess g

Sesamolin (Standard) is a reference standard for research and analysis in studies involving Sesamolin. 1. Sesamolin and Sesamin has neuroprotective effect. 2. Sesamolin protects microglia against H2O2-induced cell injury, by inhibiting of p38 MAPK and caspase-3 activation and ROS production. 3. Sesamolin and Sesamin can significantly attenuate the excess generation of nitric oxide in lipopolysaccharide-stimulated rat primary microglia cells.