sativa

Octyl acetate (Acetic acid octyl ester) is the acetate ester of octan-1-ol. It has a role as a plant metabolite.Acetic acid octyl ester is present in citrus peel oils.

Thymoquinone (NSC 2228) is a compound be found in herbs and spices with anti-inflammatory and anti-oxidant effects.

Sativanone is a useful organic compound for research related to life sciences and the catalog number is T124356.

Isosativan is a natural product discovered in Trifolium hybridum that activates the mTORC2/AKT pathway in diabetic rats and inhibits the muscle atrophy genes Atrogin-1 and MuRF1.

Sativan possesses a broad spectrum of antimicrobial activity against bacteria and phytopathogenic fungi, it exhibits antituberculosis activity against Mycobacterium tuberculosis H37Rv, with the MIC value of 50 ug/mL.

6-Hydroxyisosativan is a natural product for research related to life sciences. The catalog number is TN5455 and the CAS number is 2172624-69-8.

(-)-Sativan is a phytoalexin.

Isosativanone is a natural product for research related to life sciences. The catalog number is TN5543 and the CAS number is 82829-55-8.

Geranyl acetate is a monoterpene that has been found in C. sativa with diverse biological activities.

Olivetolic acid (OLA) is a precursor of cannabinoids from Cannabis sativa and has shown anticonvulsant activity in a mouse model of Dravet syndrome.Olivetolic acid has potential antimicrobial activity.

Camalexin, a phytoalexin isolated from (Camelina sativa), exhibits antifungal, antibacterial, antiproliferative, and anticancer activities, and can induce ROS production.

Tricin 7-O-glucuronide is a flavonoid from Alfalfa (Medicago sativa L.).

PPO-IN-17 (Compound 6R) functions as an inhibitor of protoporphyrinogen IX oxidase (PPO), effectively inhibiting tobacco PPO (NtPPO) with a Ki of 30.34 nM. This compound demonstrates herbicidal activity, achieving an inhibition rate greater than 95% against E. crus-galli, D. sanguinalis, M. sativa, and C. canadensis at a concentration of 37.5 g/hm2. Additionally, PPO-IN-17 shows no toxicity to rice at 75 g/hm2 and to bees at 6400 mg/kg.

Alpha-Hederin (Tauroside E) is a water-soluble pentacyclic triterpenoid saponin found in the seeds of Nigella sativa, with hemolytic and apoptotic properties.

β-Cembrenediol (β-CBT) is a natural product from tobacco plants that is found in cigarette smoke condensate. β-CBT inhibits induction of the early antigen of Epstein-Barr virus (EA-EBV) by 12-O-tetradecanoylphorbol-13-acetate (TPA) in vitro (IC50 = 21.9 μM). It inhibits tumor promoting effects of TPA on 7,12-demethylbenz[a]anthracene-induced papilloma formation in vivo. β-CBT is also released into soil by flue-cured tobacco plants and exerts autotoxicity as well as phytotoxic activity against L. sativa seedlings.

Pestalotin is a fungal metabolite originally isolated from P. cryptomeriaecola with diverse biological activities. It induces reducing sugar release in embryoless rice endosperms when used at concentrations ranging from 3 to 100 mg/L and enhances growth of rice seedlings (O. sativa) when used in combination with gibberellin A3 at concentrations ranging from 30 to 500 mg/L. Pestalotin has antifungal activity, reducing the growth of C. albicans, C. neoformans, T. rubrum, and A. fumigatus (MICs = 12.5, 50, 50, and 50 μg/ml, respectively). It is cytotoxic to HL-60, MKN45, LoVo, and A549 cells (IC50s = 64.87-182.92 μM). Pestalotin has been used as a standard for dereplication of natural products.

C18-HSL is one of four lipophilic, long acyl side-chain-bearing N-acylated homoserine lactones (AHLs) produced by the LuxI AHL synthase homolog SinI, involved in quorum sensing signaling in S. meliloti, a nitrogen-fixing bacterial symbiont of the legume [M. sativa]. C18-HSL and other hydrophobic AHLs tend to localize in relatively lipophilic cellular environments and cannot diffuse freely through the cell membrane. These long-chain N-acylhomoserine lactones may be exported from cells by efflux pumps or transported between communicating cells via extracellular outer membrane vesicles. Quorum sensing, a regulatory system used by bacteria to control gene expression in response to cell density, manifests in phenotypes such as biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release, and detection of small diffusible signal molecules called autoinducers, including AHLs, which vary in acyl group length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of carbon-carbon double bonds, conferring signal specificity through LuxR family transcriptional regulators. Regulation of bacterial quorum sensing signaling to inhibit pathogenesis represents a novel approach to antimicrobial therapy in treating infectious diseases.

Usaramine (Mucronatine) demonstrates phytotoxicity against Lactuca sativa var. Carrascoy (lettuce) assessed as inhibition of seed germination at 50 ug/cm2 after 24 hr.

Solidagonic acid, by inhibiting HSET motor activity, promotes the conversion of abnormal monopolar spindles to bipolar configurations, effectively suppressing fission yeast cell death and facilitating the mitotic spindles' reversion from monopolar to bipolar morphology. Additionally, this compound demonstrates growth inhibitory effects on the seedlings of Lactuca sativa L. and Lolium multiflorum Lam [1] [2].

Flaccidoside III, a flavonoid and triterpenoid compound extracted from the aerial parts of N. sativa (Ranunculaceae), demonstrates inhibition of α-Glucosidase (IC50: 256.7 μM) and exhibits potential antioxidant and antidiabetic properties [1].

Cannflavin A, isolated from Cannabis sativa L., exhibits anti-cancer, neuroprotective, and anti-inflammatory activities by inhibiting Aβ1-42 aggregation and kynurenine-3-monooxygenase (KMO), as well as inducing apoptosis through caspase-3 cleavage [1] [2] [3] [4].

"PDS-IN-1 potently inhibits Oryza sativa phytoene desaturase (OsPDS), exhibiting herbicidal activity [1]."

(R)-Citronellol ((R)-(+)-β-Citronellol) is found in herbs and spices, as well as bilberry. (R)-Citronellol is a constituent of black cumin (Nigella sativa) seeds. (R)-Citronellol is a common constituent of plant oils, especially in the Rutaceae.

Cannflavin C, also referred to as compound 5, is extractable from Cannabis sativa and exhibits antioxidant activity [1].