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By Target- E1/E2/E3 Enzyme
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Results for "
rnf5 inhibitor inh 02
" in TargetMol Product Catalog- Inhibitors & Agonists2
RNF5 inhibitor inh-02
RNF5 inhibitor inh-02
T35883324579-65-9
RNF5 inhibitor inh-02, a potent E3 ubiquitin ligase RNF5/RMA1 inhibitor, demonstrates significant efficacy in rescuing F508del-CFTR with an EC50 of 2.2 uM in bronchial epithelial cells homozygous for the F508del mutation. This compound is valuable for cystic fibrosis research[1].
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RNF5 agonist 1
T20351669909-92-8
RNF5 agonist 1 (analog-1), a structural analog of the RNF5 inhibitor inh-02, is a potent RNF5 agonist. In CFBE41o- cells expressing F508del-CFTR, RNF5 agonist 1 enhances the ubiquitination of ATG4B.
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