rifamycin

Rifamycin, a natural antibiotic, inhibits prokaryotic DNA-dependent RNA synthesis and protein synthesis, leading to the block of RNA-polymerase transcription initiation.

Rifamycin sodium (Rifamycin sodium salt) salt is an antibiotic that inhibits bacterial DNA-dependent RNA polymerase. It is effective against Gram-positive bacteria.

Rifamycin S is a potent DNA-dependent RNA polymerase inhibitor,is a quinone and an antibiotic agnet against Gram-positive bacteria

Rifamycin Y is an antibiotic that inhibits RNA polymerase. It is used in the study of Methicillin-resistant Staphylococcus aureus (MRSA) infections.

Rifamycin SV, a natural antibiotic, blocks RNA-polymerase transcription initiation, modulating ß2m aggregation; inhibits prokaryotic DNA-dependent RNA synthesis and protein synthesis.

Rifamycin W exhibits activity against Gram-positive bacteria.

Rifamycin L exhibits antibacterial properties.

3-Formyl rifamycin is a degradation product of Rifampicin, with antibacterial activity.

Rifamycin O is a useful organic compound for research related to life sciences. The catalog number is T65421 and the CAS number is 14487-05-9.

Rifampicin (Rifamycin AMP) is a broad-spectrum antibiotic. Rifampicin has a strong antibacterial effect against Mycobacterium tuberculosis and is also effective against gram-positive and gram-negative bacteria and viruses.

Rifampicin-D8 is a deuterium-labelled compound of rifampicin, which can be used for isotope tracing. Rifampicin (T0681) is a broad-spectrum antibiotic that primarily exerts its antibacterial activity by inhibiting bacterial DNA-dependent RNA polymerase.

Rifampin-BSA is a hapten-carrier protein conjugate formed by binding Rifampin to BSA (bovine serum albumin). It enhances Rifampin-induced immune responses by combining a hapten with a protein adjuvant, commonly used in vaccine or antibody preparation studies.

31-Homorifamycin W is an antibiotic discovered in Amycolatopsis mediterranei.

3-Hydroxyrifamycin S is an ansamycin antibiotic that exhibits strong activity against Gram-positive bacteria, while its effectiveness against Gram-negative bacteria is relatively limited.

Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. Rifaximin binds to the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting bacterial RNA synthesis and bacterial cell growth.

Rifapentine (Rifapentinum) is a long-acting, cyclopentyl-substituted derivative of rifamycin used to treat mycobacterium infections.

dmDNA31 is a rifamycin antibiotic that can inhibit the DNA-dependent RNA polymerase of bacteria and has strong bactericidal activity against Staphylococcus aureus.

Reprimun has a large spectrum antibiotic activity that contains an oxyminomethyl rifamycin-SV derivative as the active substance.

Rifametane is a new semi-synthetic rifamycin, an antibiotic produced naturally by the bacterium Amycolatopsis rifamycinica.

Rifamexil is a rifamycin (antibiotic produced naturally by the bacterium Amycolatopsis rifamycinica) derivative.

Tolypomycin R is a rifamycin derivative.

25-Desacetyl rifampicin is a major active metabolite of the rifamycin antibiotic rifampicin .125-Desacetyl rifampicin is active againstM. smegmatis(MIC99= 2.66 μM). 1.Kigondu, E.M., Njoroge, M., Singh, K., et al.Synthesis and synergistic antimycobacterial screening of chlorpromazine and its metabolitesMed. Chem. Commun.5502-506(2014)

AF-013 is a rifamycin derivative -- specifically an O-n-octyloxime of 3-formylrifamycin SV -- which acts as an inhibitor of nucleic acid polymerases.

CGP7040 is a rifamycin analogue, is a protein 50S ribosomal subunit inhibitor that was being developed by Novartis.