quinolinic acid

Quinolinic acid (QUIN) is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway.

Quinolinic acid-13C4,15N is an isotopically labeled form of quinolinic acid. Quinolinic acid (T4096) is an endogenous agonist of N-methyl-D-aspartate (NMDA) receptors, with potential to regulate NMDA neuronal damage and dysfunction.

Quinolinic acid-D3 is the deuterated form of Quinolinic acid. Quinolinic acid (T4096) acts as an endogenous N-methyl-D-aspartate receptor (NMDA receptor) agonist. It is synthesized from L-tryptophan via the kynurenine pathway, thus holding potential for modulating neuronal injury and dysfunction associated with N-methyl-D-aspartate.

Quinolinic acid (Standard) is a reference standard for research and analysis in studies involving Quinolinic acid. Quinolinic acid (QUIN) is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway.

Quinolinic Acid-[13C4, 15N] (Standard) is a reference standard of Quinolinic Acid-[13C4, 15N] intended for quantitative analysis, quality control, and related biochemical research applications.

Quinolinic Acid-D3 (Standard) is a reference standard of Quinolinic Acid-D3 intended for quantitative analysis, quality control, and related biochemical research applications. Quinolinic acid-d3 is the deuterated form of Quinolinic acid. Quinolinic acid acts as an endogenous N-methyl-D-aspartate receptor (NMDA receptor) agonist. It is synthesized from L-tryptophan via the kynurenine pathway, thus holding potential for modulating neuronal injury and dysfunction associated with N-methyl-D-aspartate.

NMDA receptor agonist

Ac-YVAD-CHO (L 709049) is a selective and potent tetrapeptide interleukin 1β-converting enzyme (ICE) and caspase-1 (ICE)-like protease inhibitor with anti-inflammatory activity, inhibits cancer cell growth, and inhibits the production of mature IL-lβ. Ac-YVAD-CHO attenuates quinolinic acid-induced p53 increase and apoptosis in rat striatum.

Ac-Leu-Val-Lys-Aldehyde is a potent inhibitor of cathepsin B, with an inhibitory concentration (IC50) of 4 nM. It significantly reduces quinolinic acid-induced cell death in the striatum and results in the accumulation of LC3-II [1].