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By Target- HCV Protease
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Results for "
psi 7977
" in TargetMol Product Catalog- Inhibitors & Agonists5
- Isotope Products1
Sofosbuvir
PSI-7977, GS 7977
T66761190307-88-0
Sofosbuvir (GS 7977) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatment of chronic hepatitis C.
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Sofosbuvir D6
PSI-7977 D6,GS-7977 D6
T12955
Sofosbuvir D6 is the deuterium labeled Sofosbuvir. Sofosbuvir is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity.
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Sofosbuvir impurity H
T12963
Sofosbuvir impurity H, a diastereoisomer of Sofosbuvir (PSI-7977), is an impurity of Sofosbuvir, which is an HCV RNA replication inhibitor with potent anti-hepatitis C virus activity.
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PSI-7409 tetrasodium
T138521621884-22-7
PSI-7409 tetrasodium, the active 5'-triphosphate metabolite of sofosbuvir (PSI-7977), exhibits specific inhibitory activity against NS5B polymerases of various genotypes, with IC50s being 1.6 μM for GT 1b_Con1, 2.8 μM for GT 2a_JFH1, 0.7 μM for GT 3a, and 2.6 μM for GT 4a, respectively.
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