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By Target- HIV Protease
- NF-κB(1)
- PKC(1)
- Ras(1)
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Results for "
prostratin
" in TargetMol Product Catalog- Inhibitors & Agonists1
- Natural Products1
prostratin
12-Deoxyphorbol-13-acetate
T2144160857-08-1
Prostratin (12-Deoxyphorbol-13-acetate) is an orally active protein kinase C (PKC) activator with a Ki value of 12.5 nM.As an NF-κB activator, Prostratin activates HIV gene expression in T cells.Prostratin inhibits the growth of acute myeloid leukemia (AML) cell lines and enhances cytarabine-induced AML cell differentiation. In addition, Prostratin induced KRAS phosphorylation and inhibited the growth of KRAS-mutated tumors.
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