propranolol

Propranolol hydrochloride is a widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse

(R)-Propranolol hydrochloride (Dexpropranolol hydrochloride) is the less active enantiomer of the anti-adrenoceptor (β-adrenoceptor) antagonist propranolol. Propranolol is a nonselective β-adrenergic receptor (βAR) antagonist with a high affinity for β1AR and β2AR with Ki values of 1.8 nM and 0.8 nM, respectively.

rac-Propranolol-D7 is a 2H-labeled Rac-Propranolol. Propranolol (TPL0294) is an effective β-adrenergic receptor (βAR) antagonist that inhibits β1AR and β2AR, used in cardiovascular and metabolic disease research.

4-Methoxy propranolol-d7 is a deuterium-labeled version of 4-Methoxy propranolol.

4-Hydroxypropranolol-D7 hydrochloride is deuterium-labeled 4-Hydroxypropranolol hydrochloride. 4-Hydroxypropranolol hydrochloride (T10150) is an active metabolite of Propranolol, with a potency comparable to Propranolol. It inhibits β1- and β2-adrenergic receptors (pA2s: 8.24 and 8.26).

4-Hydroxypropranolol hydrochloride is an active metabolite of Propranolol, with a potency comparable to Propranolol. It inhibits β1- and β2-adrenergic receptors (pA2s: 8.24 and 8.26).

Propranolol-D7 hydrochloride is a deuterated isotope marker of Propranolol hydrochloride (TMSM-1966), which can be used for isotope tracing. Propranolol is a non-selective beta-blocker used for hypertension research

(S)-(-)-Propranolol hydrochloride, an adrenergic receptor antagonist, exhibits potential anticancer activity and may enhance the prognosis of burn patients.

(±)-4-hydroxy Propranolol β-D-glucuronide is a metabolite of (±)-4-hydroxy propranolol , which is a metabolite of propranolol. The apparent half-life of (±)-4-hydroxy propranolol β-D-glucuronide is similar to propranolol and 4-hydroxy propranolol. Propranolol is a β-adrenergic antagonist, and the active enantiomer, (S)-(-)-propranolol , has log Kd values of -8.16, -9.08, and -6.93 for β1, β2, and β3, respectively.

rac-7-hydroxy Propranolol (hydrochloride) is a ring-hydroxylated isomer and metabolite of propranolol that is an antagonist at β-adrenergic receptors (0.95 potency relative to propranolol). It also demonstrates potent vasodilator activity (0.20 potency relative to propranolol; pA2 = 7.58).

5-hydroxy Propranolol is a metabolite of propranolol , a β-adrenergic receptor antagonist. Propranolol is primarily metabolized in the liver, with cytochrome P450 isoform 2D6 directing ring hydroxylation and the generation of 5-hydroxy propranolol and related metabolites.

Propranolol glycol, a metabolite of propranolol, exhibits transient anticonvulsant activity.

Propranolol-D7 (ring-D7) is a deuterated form of Propranolol (TPL0294) hydrochloride, which is a non-selective β-adrenergic receptor (βAR) antagonist with high affinity for both β1AR and β2AR, having Ki values of 1.8 nM and 0.8 nM, respectively. Propranolol (TPL0294) hydrochloride inhibits the binding of [3H]-DHA to rat brain membrane preparations with an IC50 of 12 nM. It is applicable in research related to hypertension, pheochromocytoma, myocardial infarction, arrhythmia, angina, and hypertrophic cardiomyopathy.

4-Hydroxy propranolol-D7 hydrochloride is a deuterated compound of 4-Hydroxy propranolol hydrochloride (T10150). 4-Hydroxy propranolol hydrochloride has a CAS number of 14133-90-5. 4-Hydroxypropranolol hydrochloride is an active metabolite of Propranolol, with a potency comparable to Propranolol. It inhibits β1- and β2-adrenergic receptors (pA2s: 8.24 and 8.26).

Propranolol glucuronide-d6 is the deuterium-labeled form of Propranolol glucuronide.

Propranolol hydrochloride (Standard) is the standard substance of Propranolol hydrochloride, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Propranolol hydrochloride is a widely used non-cardioselective beta-adrenergic antagonist. Propranolol has been used for MYOCARDIAL INFARCTION; ARRHYTHMIA; ANGINA PECTORIS; HYPERTENSION; HYPERTHYROIDISM; MIGRAINE; PHEOCHROMOCYTOMA; and ANXIETY but adverse effects instigate replacement by newer drugs.

4-Hydroxy Propranolol HCL (Standard) is a reference standard for research and analysis in studies involving 4-Hydroxy Propranolol HCL. 4-Hydroxypropranolol hydrochloride is an active metabolite of Propranolol, with a potency comparable to Propranolol. It inhibits β1- and β2-adrenergic receptors (pA2s: 8.24 and 8.26).

Propranolol‑D7 hydrochloride (Standard) is a reference standard of Propranolol‑D7 Hydrochloride intended for quantitative analysis, quality control, and related biochemical research applications

Propranolol-[D5] (Standard) is a reference standard of Propranolol-[D5] intended for quantitative analysis, quality control, and related biochemical research applications.

4-Hydroxypropranolol-D7 Hydrochloride (Standard) is a reference standard of 4-Hydroxypropranolol-D7 Hydrochloride intended for quantitative analysis, quality control, and related biochemical research applications.

Norpropranolol hydrochloride is the active metabolite of Propranolol.

(±)-Desisopropylpropranolol (N-Desisopropylpropranolol) is a metabolite of Propranolol. Propranolol acts as a non-selective β-adrenergic receptor (βAR) antagonist with high affinity for both β1AR and β2AR, having Ki values of 1.8 nM and 0.8 nM, respectively. It inhibits the binding of [3H]-DHA to rat brain membrane preparations with an IC50 of 12 nM. Propranolol is used in studies related to hypertension, pheochromocytoma, myocardial infarction, arrhythmias, angina pectoris, and hypertrophic cardiomyopathy.

Phosphatase-IN-1 (compound II-8), a propranolol derivative, acts as an inhibitor of phosphatidate phosphatase (Pah). It binds to MoPah1 with an affinity constant of 19.8 μM, demonstrating growth inhibition of plant pathogens and anti-fungal properties, while exhibiting no toxicity towards rice seedlings and wheat heads [1].

(R)-(+)-Atenolol ((R)-Atenolol) is a cardioselective beta-1 adrenergic blocker, which properties are similar to propranolol, but without a negative inotropic effect.