propionibacterium

SY-640 is an Acetamide derivative. SY-640 exhibits potent hepatoprotective effect. SY-640 reduces liver injury in mice induced by Propionibacterium acnes and Lipopolysaccharide.

Azelaic acid (Anchoic acid) is a component of hair and skin conditioners and is produced by the ozonolysis of oleic acid. Azelaic acid has bacteriostatic activity against Propionibacterium acnes and Staphylococcus epidermidis by inhibiting protoprotein synthesis in microbial cells. Azelaic acid also has the ability to inhibit pigmentation due to its free radical scavenging action.

1-Decanol inhibits various bacteria and fungi, including Candida albicans, Penicillium, Aspergillus niger, Bacillus subtilis, Propionibacterium, and others.

3-Octyl alcohol can inhibit Propionibacterium and has potential antibacterial activity, making it widely used in biochemical experiments and drug synthesis research.

Vebufloxacin (OPC-7251) shows potent antibacterial activity against gram-positive and -negative bacteria, including Staphylococcus aureus and Pseudomonas aeruginosa. It has potent activity characteristically against Propionibacterium acnes.

Calcium Linoleate, a calcium salt of linoleic acid, exhibits bactericidal activity against Staphylococcus epidermidis (S. epidermidis) and shows antibacterial effects on Staphylococcus aureus (S. aureus) and Propionibacterium acnes (P. acnes).

(±)15-HEPE is a racemic mixture of monohydroxy fatty acids 15(R)-HEPE and 15(S)-HEPE, with antibacterial activity, inhibiting Propionibacterium acnes and Staphylococcus aureus.

Coproporphyrin III dihydrochloride, a bioactive compound secreted by nostril- and skin-associated Propionibacterium species, promotes the aggregation of Staphylococcus aureus during early stationary phase growth at a low pH of 4-6. In addition, it facilitates plasma-independent biofilm formation by S. aureus on non-living surfaces. This compound could play a crucial role in mediating the accumulation and biofilm development of S. aureus in nasal passages or other locations where both Propionibacterium and S. aureus coexist.

SC-23110 is an effective anti-acne agent that inhibits the growth of Propionibacterium acnes (P. acnes), an organism linked to acne and commonly associated with the pathogenesis of inflammatory pustules lesions.