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(2)
By Target- p53
- Autophagy(1)
- Ferroptosis(1)
- HSP(1)
- Others(1)
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Results for "
pifithrin-β
" in TargetMol Product Catalog- Inhibitors & Agonists3
Pifithrin-β hydrobromide
Cyclic Pifithrin-α hydrobromide, Cyclic PFT-α, Pifithrin-β, PFT-β, PFT β (hydrobromide)
T3637511296-88-1
Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Active in vivo; protects mice from the side-effects of Y therapy associated with p53 induction. Supresses self-renewal of embryonic stem cells. Also aryl hydrocarbon receptor (AHR) agonist, causes upregulation of AHR target gene CYP1A1 (EC50 = 1.1 μM).
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Pifithrin-μ
PFTμ, NSC 303580, 2-Phenylethynesulfonamide
T621064984-31-2
Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.
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