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pi 55

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PI-55
6-(2-hydroxy-3-methylbenzylamino)purine
T603901122579-42-3
PI-55 (6-(2-hydroxy-3-methylbenzylamino)purine) is a cytokinin receptor inhibitor that exhibits structural similarity to 6-benzylaminopurine (BAP). It competitively inhibits BAP binding on the specific Arabidopsis receptors CRE1/AHK4 and AHK3. Furthermore, PI-55 effectively suppresses cytokinins-induced haustorium formation and enhances parasite aggressiveness [1].
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PI3K-IN-55
T88935
PI3K-IN-55 (Compound 6a) serves as a potential inhibitor of PI3K. It modulates the PI3K/Akt/p53 signaling pathway and inhibits proliferation in cancer cell lines A549, Hela, HepG2, MCF-7, and HT-29, with IC50 values ranging from 1.03 to 6.78 μM. Additionally, PI3K-IN-55 induces apoptosis in MCF-7 cells.
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