pi 2

Serpin A1b Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 70.2 kDa.

Expression system: Baculovirus Insect Cells
Length: 1-379, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 1-380, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 2-416, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 1-390, Full Length
Activity: Not Tested

Expression system: E. coli
Length: 574-689, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 28-491, Full Length of Mature Protein
Activity: Not Tested

CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. CD19 primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase. CD19 Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. Defects in CD19 are the cause of immunodeficiency common variable type 3 (CVID3) which is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen.

Expression system: HEK293 Cells
Length: 20-397, Full Length of Mature Protein of Isoform 2
Activity: Not Tested

Large-pool solvent detergent (SD) plasma for transfusion exhibits reduced alpha 2-antiplasmin (alpha2-AP; SERPINF2) functional activity. The reason for the loss of alpha2-AP has not been described and could be due to the SD incubation itself and or to the processing steps implemented to remove the solvent and the detergent.

Expression system: HEK293 Cells
Length: 1-491, Full Length
Activity: Enzyme Activity

Serpins are the largest and most diverse family of serine protease inhibitors which are involved in a number of fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner.Mouse SerpinB8, also known as Cytoplasmic antiproteinase 2, Peptidase inhibitor 8, SerpinB8, PI-8, SERPINB8 and CAP2, is a member of the Serpin superfamily. SERPINB8 was broadly expressed. In normal neuroendocrine tissues, strongest SerpinB8 expression was detected in islets of Langerhans of the pancreas. Moderate SerpinB8 expression was observed in neuroendocrine cells of the thyroid, adrenal cortex, colon, and pituitary gland. In the pancreas, SerpinB8 is specifically expressed by insulin-producing beta cells, and can be used as an additional diagnostic immunohistochemical marker. Mouse SerpinB8 distribution alters during kidney regeneration, possibly to control a prohormone convertase involved in inflammation or tissue repair.

Expression system: HEK293 Cells
Length: 1-405, Full Length
Activity: Not Tested

Expression system: Baculovirus Insect Cells
Length: 2-376, Partial
Activity: Not Tested

Expression system: E. coli
Length: 1-218, Full Length
Activity: Not Tested

Expression system: Baculovirus Insect Cells
Length: 1-390, Full Length
Activity: Not Tested