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phorbol 12,13 dibutyrate

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  • Inhibitors & Agonists
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Phorbol 12,13-dibutyrate
Phorbol dibutyrate, PDBu
T1652637558-16-0In house
Phorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator that inhibits α1-adrenoceptor-mediated positive inotropic effects in a concentration-dependent manner, induced by contraction of isolated rabbit vascular smooth muscle.
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Lyso-monosialoganglioside GM2 ammonium
LysoGM2 ammonium
T211829
Lyso-monosialoganglioside GM2 (LysoGM2) ammonium is a lysosomal sphingolipid and an inhibitor of protein kinase C, with an IC50 value of 50 μM. It inhibits the binding of protein kinase C to Phorbol 12,13-dibutyrate. Additionally, LysoGM2 ammonium serves as a specific biomarker for GM2 gangliosidosis and is utilized in the study of sphingolipidosis.
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