phenylpropanoid

3,4-Dimethoxyphenol (4-Hydroxyveratrole) is an active biochemical.

Plantamajoside (Y0160) has anti-hepatotoxic, anti-inflammatory, antinociceptive activities, improving sexual function and antioxidant activity.

Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM, it also exhibits great inhibitory effects on rat lens aldose reductase with IC50 values of 0.85 μM.Poliumos

Regaloside B, a phenylpropanoid isolated from Lilium longiflorum, exhibits anti-inflammatory activity by inhibiting the expression of iNOS (inducible nitric oxide synthase) and COX-2 (cyclooxygenase-2).

Lycibarbarphenylpropanoid B, a phenylpropanoid derived from wolfberry, demonstrates potent antioxidant properties. It has a notable oxygen radical absorbance capacity, reflected by an ORAC value of 3.18 μmol Trolox/μmol (Trolox is a standard reference antioxidant, indicating that each μM of Lycibarbarphenylpropanoid B has antioxidant activity equivalent to 3.18 μM Trolox).

Coniferaldehyde (Ferulaldehyde) is a member of the class of cinnamaldehydes that is cinnamaldehyde substituted by a hydroxy group at position 4 and a methoxy group at position 3. It has a role as an antifungal agent and a plant metabolite. It is a member of cinnamaldehydes, a phenylpropanoid and a member of guaiacols. It derives from a cinnamaldehyde.

4-Methoxycinnamic acid is an unusual phenylpropanoid involved in phenylphenalenone biosynthesis in Anigozanthos preissi.

3,4-(Methylenedioxy)cinnamic acid (3-(Benzo[d][1,3]dioxol-5-yl)acrylic acid) is a plant-derived compound first extracted from roots of Asparagus officinalis and further characterized as an allelochemical.

5-Hydroxyferulic acid is an important hydroxycinnamic acid compound and a metabolite in the phenylpropanoid pathway. It acts as a precursor for the biosynthesis of sinapic acid and functions as a non-esterified substrate for COMT.

Neohelmanthicin B, a phenylpropanoid isolated from Thapsia garganica, demonstrates cytotoxic properties against EL4, S180, and MCF7 cell lines, with respective IC50 values of 10, 5, and 12 μM [1].

Neohelmanthicin A (compound 3A), a phenylpropanoid with antitumor properties, exhibits IC50 values of 0.13 μM, 7 μM, and 23 μM against leukemia cell line EL4, breast cancer cell line S180, and breast cancer cell line MCF7, respectively [1].

Chavicol β-D-glucoside, a phenylpropanoid heteroside, can be isolated from subspecies of Cedronella canariensis [1].

7′-Methoxylariciresinol, a phenylpropanoid, can be isolated from Crataegus pinnatifida [1].

2,4-Dihydroxyallylbenzene-2-O-β-D-glucopyranoside is a phenylpropanoid glycoside [1].

Cuneataside E is a phenylpropanoid glycoside compound identified in Lespedeza cuneata. It exhibits protective effects against the toxicity induced by N-acetyl-p-aminophenol (APAP) in the human liver cancer cell line HepG2. Cuneataside E holds potential for research in liver diseases.

Tadehaginoside E is a phenylpropanoid glycoside found in the medicinal plant Tadehagi triquetrum, known for its various biological activities.

9-O-β-D-Glucopyranosyl-3,4-dimethoxy-cinnamic acid is an orally bioactive phenylpropanoid glycoside identified in Microlepia pilosissima, acting as an antioxidant. It demonstrates DPPH radical scavenging activity with an ED50 value of 38.1 μM. This compound holds potential for research in oxidative stress-related conditions such as inflammation and liver damage.

(E)-Tadehaginoside is the E isomer of Tadehaginoside, a phenylpropanoid glycoside. It plays a role in modulating lipogenesis and glucose consumption, while exhibiting antioxidant properties. By regulating the Nrf2 and NF-κB signaling pathways in hepatocytes, Tadehaginoside contributes to liver protection, preventing oxidative stress damage and inflammation. It is utilized in studies on obesity and diabetes.

Acoraminol A is a stereoisomer of phenylpropanoid, distinct from Acoraminol B, and can be isolated from the methanol extract of Acorus calamus rhizomes. Acoraminol A exhibits mild cytotoxicity against several human tumor cell lines (IC50>30 μM).

Tadehaginoside, a phenylpropanoid glycoside, regulates adipogenesis and glucose consumption and possesses antioxidant properties. By modulating the Nrf2 and NF-κB signaling pathways in hepatic cells, Tadehaginoside acts as a liver protectant, preventing oxidative stress damage and inflammation. It is applicable in the study of obesity and diabetes.

Brandioside (2'-Acetylpoliumoside), a phenylpropanoid glycoside obtainable from Callicarpa dichotoma Raeuschel, Verbenaceae, has antioxidant activity, attenuates glutamate-induced neurotoxicity, and can be used in the study of diabetes mellitus.

Meloside A (Isovitexin 2''-O-β-D-glucoside) is a phenylpropanoid extracted from barley, exhibiting antioxidant and protective properties against excess UV-B radiation, and has been linked to resistance to pathogens.

Verbasoside (Decaffeoyl acteoside) is a phenylpropanoid isolated from the roots of Rehmannia glutinosa (Gaertn.) DC.

Ethyl chlorogenate is a phenylpropanoid natural product with inhibitory activity against rat aldose reductase (IC₅₀ = 1.5 µM).