peptide t tfa

Peptide T (TFA), an octapeptide derived from the V2 region of HIV-1 gp120, functions as a ligand for the CD4 receptor, thereby effectively inhibiting HIV binding to the CD4 receptor.

ELAAWCRWGFLLALLPPGIAG TFA (P5), a 21-amino-acid peptide (aa 5-25) originating from the rat HER2 neu protein, has been shown to elicit cytotoxic T lymphocyte (CTL) responses in mice with HER2-positive tumors [1].

Tetanus Toxin (830–844) TFA is a bioactive peptide. It acts as a CD4+ T cell epitope derived from tetanus toxin (TT830–844). This hybrid CD4+ T cell epitope binds to various HLA-DRB molecules, potentially activating CD4+ T cell responses in a broad population.

LCMV gp33-41 (TFA), an 11-amino-acid carboxyl-extended peptide, comprises a lymphocytic choriomeningitis virus sequence that is presented by MHC class I H-2Db molecules to cytotoxic T lymphocytes [1].

LCMV gp33-41 (TFA), the carboxyl-extended 11-aa-long peptide, is an lymphocytic choriomeningitis virus sequence restricted by MHC class I H-2Db molecules and presented to cytotoxic T lymphocytes[1].

Acyline TFA, a gonadotropin-releasing hormone (GnRH) peptide analogue, functions as a GnRH antagonist, effectively suppressing gonadotropin and testosterone (T) levels [1].

CD31 TFA, also known as platelet endothelial cell adhesion molecule-1 (PECAM-1), functions as the specific receptor for Clostridium perfringens beta-Toxin (CPB) in endothelial cells. It is recognized as an ER-MP12 antigen and plays a pivotal role in connecting mechanical stress, metabolism, and inflammation. Additionally, the CD31 TFA peptide facilitates the phosphorylation of CD31 ITIM 686 and SHP2, further inhibiting TCR-induced T-cell activation [1]-[5].

Myelin Basic Protein (87-99) TFA, an encephalitogenic peptide, promotes basic protein-specific T cell proliferation and induces Th1 polarization in peripheral blood mononuclear cells, contributing to the pathogenesis of multiple sclerosis (MS) [1] [2].

Caerin 1.1 TFA, a host defense peptide derived from the Australian tree frog Litoria's glandular secretions, exhibits anti-proliferative effects on HeLa cells and induces apoptosis. Additionally, it has the potential to augment adaptive T cell immune responses [1].