paroxetine

Paroxetine is a inhibitor of serotonin uptake that is effective in the treatment of depression.

Paroxetine hydrochloride hemihydrate (Paxil) is an effective and selective serotonin reuptake inhibitor (SSRI).

Paroxetine hydrochloride (Paroxetine HCl) is a serotonin uptake inhibitor that is effective in the treatment of depression.

Paroxetine maleate is a selective inhibitor of serotonin reuptake and an antidepressant.

Paroxetine Mesylate, the mesylate salt form of paroxetine, is a phenylpiperidine derivative and a selective serotonin reuptake inhibitor (SSRI) with anxiolytic and antidepressant properties.

N-methyl Paroxetine is a derivative of the selective serotonin reuptake inhibitor (SSRI) antidepressant paroxetine that inhibits [3H]paroxetine binding to rat cortical membranes (Ki = 4.3 nM). It inhibits serotonin uptake in rat brain synaptosomes with an IC50 value of 22 nM. N-methyl Paroxetine has been used as a precursor in the synthesis of paroxetine and is a potential impurity in commercial preparations of paroxetine.

Desmethylene Paroxetine hydrochloride is a non-conjugated metabolite of Paroxetine, a catechol intermediate.

rac-Paroxetine-d4 Hydrochloride is a deuterated compound of rac-Paroxetine Hydrochloride. rac-Paroxetine Hydrochloride has a CAS number of 78246-49-8. Paroxetine hydrochloride is a serotonin uptake inhibitor that is effective in the treatment of depression.

Paroxetine-d4 HCl is a deuterated compound of Paroxetine HCl. Paroxetine HCl has a CAS number of 78246-49-8. Paroxetine hydrochloride is a serotonin uptake inhibitor that is effective in the treatment of depression.

PIM-35, an indole derivative with properties similar to antidepressants, exhibits weaker norepinephrine uptake inhibition compared to standard compounds. Prolonged use of PIM-35 does not affect the quantity or affinity of alpha 2, beta 1-, and beta 2-adrenergic receptors. Additionally, PIM-35 influences the serotonin system, resembling antidepressant compounds like paroxetine and clomipramine.

CTP-347, a deuterated version of paroxetine, is potentially the best non-hormonal drug in its class for the treatment of hot flashes.

GRKs-IN-1 hydrochloride, Compound 14as, has remarkable potency against and selectivity for G protein-coupled receptor kinase 2 GRK2 (IC50=130 nM) and GRK5 (IC50=7.1 μM).GRKs-IN-1 hydrochloride is a derivative 14as of paroxetine, shows a 100-fold improvement in cardiomyocyte contractility assays over paroxetine[1]. [1]. Waldschmidt HV, et al. Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2Inhibitors Based on Paroxetine. J Med Chem. 2017 Apr 13;60(7):3052-3069.

Paroxol methanesulfonate is an intermediate in the synthesis of Paroxetine, a selective serotonin reuptake inhibitor.