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(2)
By Target- Ras
- MAPK(1)
- Molecular Glues(1)
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Results for "
pan ras in 1
" in TargetMol Product Catalog- Inhibitors & Agonists2
Pan-RAS-IN-1
T164321835283-94-7
Pan-RAS-IN-1 is an inhibitor of pan-Ras. It disrupts the interaction of Ras proteins and their effectors.
- $73
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QTY
Pan-RAS-IN-2
T881163034673-92-9
Pan-RAS-IN-2 (compound 6A) is an orally active molecular glue that targets RAS by inducing ternary complex formation with cyclophilin A (CYPA) and RAS in the ON state, leading to potent inhibition of downstream RAF binding and pERK signaling with an IC50 of 0.3 nM in AsPC-1 cells, Pan-RAS-IN-2 demonstrates strong antiproliferative effects in RAS-mutant cancer cell lines, supporting research into targeted therapies for colorectal and pancreatic cancers.
- $158
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