oxygenated

1. Ganoderic acid D is one of the major components in Ganoderma triterpenes. 2. Ganoderic acid D treatment for 48h inhibits the proliferation of HeLa human cervical carcinoma cells with an IC(5) value of 17.3 +/- .3 microM.

1,4-Cineole (Isocineole) is a natural, oxygenated monoterpene. 1,4-Cineole can activate both human TRPM8 and human TRPA1.

β-Cryptoxanthin is isolated from Satsuma mandarin orange with an anti-stress effect. It is an oxygenated carotenoid and an antioxidant.

8-Keto-berberine is a non-naturally occurring 11, 12-oxygenated protoberberine. It is a derivative from naturally occurring 9, 10-oxygenated protoberberine.

Lachnanthocarpone is a member of the 6-oxygenated phenylphenalenones.

Lamiophlomiol A is a highly oxygenated iridoid isolated from the roots of Lamiophlomis rotata.

N-Arachidonoyl taurine is an arachidonoyl amino acid. It is oxygenated by 12(S)- and 15(S)-lipoxygenase and is converted to 12-HETE-taurine (12-HETE-T) in murine resident peritoneal macrophages. N-Arachidonoyl taurine is an activator of the transient receptor potential vanilloid (TRPV) channels TRPV1 and TRPV4 (EC50s = 28 and 21 μM, respectively). It increases calcium flux in HIT-T15 pancreatic β-cells and INS-1 rat islet cells when used at a concentration of 10 μM and increases insulin secretion from 832/13 INS-1 pancreatic β-cells. The levels of N-arachidonoyl taurine are changed in mouse brain following administration of δ9-tetrahydrocannabinol (δ9-THC).

Carotenoid mixture is a mixture of carotenoids that contains the antioxidative and anti-inflammatory carotenoid capsanthin and the antioxidative vitamin A precursor β-carotene , as well as additional carotenoids and carotenoid esters.1,2,3,4 1.Kim, J.S., Lee, W.M., Rhee, H.C., et al.Red paprika (Capsicum annuum L.) and its main carotenoids, capsanthin and β-carotene, prevent hydrogen peroxide-induced inhibition of gap-junction intercellular communicationChem. Biol. Interact.254146-155(2016) 2.Narisawa, T., Fukaura, Y., Hasebe, M., et al.Prevention of N-methylnitrosourea-induced colon carcinogenesis in rats by oxygenated carotenoid capsanthin and capsanthin-rich paprika juiceProc. Soc. Exp. Biol. Med.224(2)116-122(2000) 3.Horie, S., Okuda, C., T., Y., et al.Purified canola lutein selectively inhibits specific isoforms of mammalian DNA polymerases and reduces inflammatory responseLipids45(8)713-721(2010) 4.Negishi, H., Ueda, Y., and Azuma, M.Antioxidant fat-soluble vitamins and lipid peroxides in serumJ. Clin. Biochem. Nutr.26227-234(1999)

3β-OH-7-Oxocholenic acid is a bile acid.1 It is also a metabolite of 7β-hydroxy cholesterol in rats. Conjugated forms of 3β-OH-7-oxocholenic acid have been found in the urine of patients with Neimann-Pick disease type C.2,3 |1. Norii, T., Yamaga, N., and Yamasaki, K. Metabolism of 7β-hydroxycholesterol-4-14C in rat. Steroids 15(3), 303-326 (1970).|2. Alvelius, G., Hjalmarson, O., Griffiths, W.J., et al. Identification of unusual 7-oxygenated bile acid sulfates in a patient with Niemann-Pick disease, type C. J. Lipid Res. 42(10), 1571-1577 (2001).|3. Maekawa, M., Omura, K., Sekiguchi, S., et al. Identification of two sulfated cholesterol metabolites found in the urine of a patient with Niemann-Pick disease type C as novel candidate diagnostic markers. Mass Spectrom. (Tokyo) 5(2), S0053 (2016).

12-oxo-13-HOME is an oxylipin derived from linoleic acid .1It is formedviaa 13-HpODE intermediate that is produced by lipoxygenase-mediated metabolism of linoleic acid.2,3,112-oxo-13-HOME has been found in corn and sunflower seedlings.4 1.Ogorodnikova, A.V., Gorina, S.S., Mukhtarova, L.S., et al.Stereospecific biosynthesis of (9S,13S)-10-oxo-phytoenoic acid in young maize rootsBiochim. Biophys. Acta1851(9)1262-1270(2015) 2.Veldink, G.A., and Vliegenthart, J.F.G.The enzymic conversions of 13-hydroperoxy-cis-9-trans-11-octadecadienoic acid into 13-hydroxy-12-oxo-cis-9-octadecenoic acidBiochem. J.110(4)58P(1968) 3.Gardner, H.W.Sequential enzymes of linoleic acid oxidation in corn germ: Lipoxygenase and linoleate hydroperoxide isomeraseJ. Lipid Res.11(4)311-321(1970) 4.Vick, B.A., and Zimmerman, D.C.Levels of oxygenated fatty acids in young corn and sunflower plantsPlant Physiol.69(5)1103-1108(1982)

Saccharothrixin F, an extensively oxygenated variant within the saccharothrixin class, exhibits antibacterial and anti-inflammatory properties.

Ganoderic acid GS-1, an extensively oxygenated lanostane-type triterpenoid, exhibits anti-HIV-1 protease activities, displaying an IC50 value of 58 μM [1].

Ganoapplanoid F, a highly oxygenated lanostane triterpenoid derived from Ganoderma applanatum, impedes lipid accumulation in adipocytes and offers potential for obesity research [1].

(±)-Lavandulol, an atypical monoterpene alcohol, undergoes biotransformation by the fungal strain Rhizopus oryzae to yield its oxygenated metabolite [1].

(±)-Lavandulol (Standard) is a reference standard for research and analysis in studies involving (±)-Lavandulol. (±)-Lavandulol, an atypical monoterpene alcohol, undergoes biotransformation by the fungal strain Rhizopus oryzae to yield its oxygenated metabolite [1].

β-Cryptoxanthin (Standard) is a reference standard for research and analysis in studies involving β-Cryptoxanthin. β-Cryptoxanthin is isolated from Satsuma mandarin orange with an anti-stress effect. It is an oxygenated carotenoid and an antioxidant.

Monensin C is an oxygenated heterocyclic polyether antibiotic. It exhibits activity against bacteria, mycobacteria, fungi, and protozoa, though it is less effective against Gram-negative bacteria. Additionally, it shows inhibitory effects on HeLa cells.

The oxygenated sterols( 26-oxygenosterols ganoderol A, ganoderol B, ganoderal A, and ganoderic acid Y) from G. lucidum can inhibit cholesterol biosynthesis via conversion of acetate or mevalonate as a precursor of cholesterol.

δ-Cadinol ((-)-Torreyol), an oxygenated sesquiterpene, is derivable from Lepechinia salviae (Lindl.) Epling.

(-)-Lavandulol is an isomer of (±)-Lavandulol. This compound is an irregular monoterpene alcohol that can be transformed by the fungus Rhizopus oryzae into corresponding oxygenated metabolites.

Succinyl-β-cycloaltrin is a modified cyclodextrin distinguished by unique chemical properties, enhancing its role as an effective solubilizing and stabilizing agent in various compounds, particularly within the pharmaceutical sector. With its hydrophobic interior and hydrophilic exterior, Succinyl-β-cycloaltrin forms stable inclusion complexes with hydrophobic molecules like drugs and nutrients. This interaction improves their solubility and bioavailability, making them more effective for therapeutic or nutritional applications.

30-Hydroxytriacontanoic acid (ω-Hydroxytriacontanoic acid) is an oxygenated fatty acid.