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oxfenicine

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  • Inhibitors & Agonists
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Oxfenicine
4-Hydroxy-L-phenylglycine
T478532462-30-9
Oxfenicine (4-Hydroxy-L-phenylglycine) is a carnitine palmitoyltransferase-1 inhibitor. Oxfenicine improves whole-body glucose tolerance and insulin sensitivity in high-fat diet-induced obese mouse with insulin resistance.
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4-Hydroxyphenylglyoxylic Acid
UK 22486
T8376715573-67-8
4-Hydroxyphenylglyoxylic acid, an active metabolite of the prodrug oxfenicine, functions as an inhibitor of carnitine palmitoyltransferase 1 (CPT1). It effectively inhibits CPT1 in isolated rat liver mitochondria at concentrations of 200 to 1,000 µM and restricts oleate oxidation in isolated rat hepatocytes.
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8-10 weeks
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