nordihydroguaiaretic acid

Nordihydroguaiaretic acid (NDGA) is a natural product, extracted from Pole Fork Kelaroa, and is a lipoxygenase (5-LOX) inhibitor (IC50=8 μM). Nordihydroguaiaretic acid possesses antioxidant and free radical scavenging properties.

Nordihydroguaiaretic acid (Standard) is the standard substance of Nordihydroguaiaretic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Nordihydroguaiaretic acid (NDGA) is a natural product, extracted from Pole Fork Kelaroa, and is a lipoxygenase (5-LOX) inhibitor (IC50=8 μM). Nordihydroguaiaretic acid possesses antioxidant and free radical scavenging properties.

Terameprocol (EM-1421) is a synthetic tetra-methylated derivative of nordihydroguaiaretic acid (NDGA) and transcriptional inhibitor with potential antiviral, antiangiogenic, and antineoplastic activities. Terameprocol showed the strongest anti-HIV activity.

Masoprocol tetrapivalate (Nordihydroguaiaretic acid tetrapivalate) is a catecholic butane metabolite and an inhibitor of the tyrosine kinase activities of IGF-1R and EGFR. It regulates tyrosine kinase signaling pathways associated with cell proliferation. Masoprocol tetrapivalate is applicable in the study of proliferative diseases, including malignant, precancerous, or benign cancers, as well as solid tumors.

Masoprocol (meso-Nordihydroguaiaretic acid) is a potent, orally active lipoxygenase inhibitor that exhibits antihyperglycemic activity, making it potentially valuable for type II diabetes research. In vivo, Masoprocol reduces glucose and hepatic triglyceride concentrations [1] [2] [3].