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Search Results for " nonhomologous "

Targets

5

Compounds

Cat No. Product Name Synonyms Targets
T10981 DCZ0415 Apoptosis , Others , NF-κB
DCZ0415 induces antimyeloma activity in vitro, in vivo and in primary cells of drug-resistant myeloma patients. DCZ0415 is a potent TRIP13 inhibitor that can impair the repair of non-homologous end junctions and inhibit ...
T1724 SCR7 pyrazine SCR7 Apoptosis , DNA/RNA Synthesis , CRISPR/Cas9
SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).
T3340 SCR7 Apoptosis , DNA/RNA Synthesis , CRISPR/Cas9
SCR7, a specific DNA Ligase IV inhibitor, blocks nonhomologous end-joining (NHEJ).
T8880 PFM01 Others
PFM01 is an inhibitor of MRE11 endonuclease. PFM01 can regulate double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ) versus homologous recombination (HR).
T60621 PFM03
PFM03 is an inhibitor of MRE11 Endonuclease that regulates DNA double-strand break repair (DSBR) by nonhomologous end-joining (NHEJ) [1].
TargetMol