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non-hdl-c

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  • Inhibitors & Agonists
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    TargetMol | Inhibitory_Antibodies
Icosabutate
PRC-4016, NST-4016
T155491253909-57-7In house
Icosabutate (NST-4016) is an orally active derivative of eicosapentaenoic acid that inhibits hepatic inflammation and fibrosis in NASH, improves cardiovascular risk profiles in statin-treated patients with residual hypertriglyceridemia, lowers triglycerides, and may be useful in studies of liver fibrosis and atherosclerosis.
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6-8 weeks
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Ebronucimab
AK102, AK 102
T806082304800-90-4
Ebronucimab (AK102) is an IgG1 antibody targeting PCSK9 that lowers LDL-C, TC, Non-HDL-C, and ApoB, and raises, HDL-C and Apo A-I for the treatment of primary hypercholesterolemia and mixed hyperlipidemia and heterozygous familial hypercholesterolemia (HeFH).
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