nh 3

NH-3 is a potent orally active thyroid hormone receptor (THR) antagonist which exhibits reversible behavior, demonstrated by an IC 50 of 55 nM. Derived from the selective thyromi-metic GC-1, NH-3 effectively inhibits the binding of thyroid hormones to their respective receptors, resulting in hindered cofactor recruitment.

Phenanthriplatin, also known as cis-[Pt(NH3)2-(phenanthridine)Cl]NO3, is a new drug candidate. It belongs to a family of platinum(II)-based agents which includes cisplatin, oxaliplatin and carboplatin. Phenanthriplatin Acts As a Covalent Poison of Topoiso

Thalidomide-O-amido-C3-NH2 TFA (Cereblon Ligand-Linker Conjugates 16 TFA) is a synthesized E3 ligase ligand-linker conjugate incorporating a Thalidomide-based cereblon ligand and a linker used in PROTAC technology.

Aminooxy-PEG3-C2-NH-Boc is a PEGylated PROTAC linker used in synthesizing PROTACs, a new class of bifunctional molecules for targeted protein degradation [1].

APN-C3-NH-Boc is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-NH-PEG3-propargyl is a PEG-based linker used in PROTACs for connecting two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Boc-NH-PEG3-sulfonic acid, a polyethylene glycol (PEG) derived linker, is utilized in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Bromoacetamido-PEG3-NH-Boc is a polyethylene glycol (PEG)-based linker compound used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Cbz-NH-PEG3-C2-acid is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands crucial for PROTAC molecule formation. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

endo-BCN-PEG3-NH-Boc is a PEG-based linker for PROTACs, joining two essential ligands integral to PROTAC molecule formation, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.

Fluorescein-PEG3-NH-Boc is a polyethylene glycol (PEG)-based proteolysis-targeting chimera (PROTAC) linker used for PROTAC synthesis[1].

Fmoc-NH-PEG3-CH2CH2COOH is a cleavable ADC linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].

N-(Azido-PEG3)-NH-PEG3-acid is a polyethylene glycol (PEG) derived linker used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

NH-bis(PEG3-azide) is a PROTAC linker of the PEG class used in the synthesis of PROTAC molecules.

NH-bis(PEG3-Boc) is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

NH-bis(PEG3-C2-NH-Boc) is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation through the ubiquitin-proteasome system within cells.

NH-bis-PEG3 is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Boc-NH-PEG3-C2-triazole-DBCO-PEG4-VC-PAB-DMEA is a double-cleavable PEG linker (3-unit and 4-unit) designed for antibody-drug conjugation (ADC).

DBCO-C3-PEG4-NH-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Fmoc-N-bis-PEG3-NH-Boc is a cleavable ADC linker compound with three PEG units, used in the synthesis of antibody-drug conjugates (ADCs)[1].

Fmoc-NH-PEG3-C2-NH2 is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands crucial for PROTAC molecule formation. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(Azido-PEG3)-N-(PEG2-NH-Boc)-PEG3-acid is a polyethylene glycol (PEG)-based linker used in the development of proteolysis targeting chimeras (PROTACs)[1].

NH-bis(PEG3-acid) is a PEG-based linker utilized in PROTACs, connecting two essential ligands crucial for creating PROTAC molecules. This linker leverages the ubiquitin-proteasome system within cells to enable selective protein degradation.

Propargyl-NH-PEG3-C2-NHS ester is a non-cleavable triethylene glycol linker featuring propargyl and N-hydroxysuccinimide (NHS) functional groups, used in the synthesis of antibody-drug conjugates (ADCs)[1].