nephroprotective

Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.

Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.

L-Ornithine hydrochloride ((S)-2,5-Diaminopentanoic acid) has an antifatigue effect by increasing the efficiency of energy consumption and promoting the excretion of ammonia. It is one of the key reactants in the urea cycle.

Lercanidipine, (S)- is an isomer of Lercanidipine, an antihypertensive compound.Lercanidipine is a dihydropyridine calcium channel blocker with long-lasting antihypertensive and nephroprotective effects.

Cinnamtannin A2 is a natural product and procyanidin tetramer that enhances GLP-1 and insulin secretion in mice. It protects against renal injury by reducing KIM-1 and NGAL expression and exhibits antioxidant activity.

PHD2/HDACs-IN-1 is a potent mixed inhibitor of PHD2/HDACs, acting on PHD2 (IC50: 1.15 μM), HDAC1 (IC50: 19.75 μM), HDAC2 (IC50: 26.60 μM), and HDAC16 (IC50: 15.98 μM). HDACs-IN-1 is a low toxicity nephroprotective agent suitable for studies of cisplatin-induced acute kidney injury (AKI).

Pitavastatin (NK-104) sodium is a potent inhibitor of hydroxymethylglutaryl-CoA (HMG-CoA) reductase and an inducer of the hepatocyte low-density lipoprotein cholesterol (LDL-C) receptor. It inhibits acetate synthesis of cholesterol in HepG2 cells and exhibits anti-atherogenic, anti-osteoarthritic, anti-asthmatic, anti-tumour, neuroprotective, hepatoprotective, and nephroprotective effects.

1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of melanogenesis. 3. Mulberroside A has anti-inflammatory antiapoptotic effects. by decreasing the expressions of tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, and IL-6 and inhibiting the activation of NALP3, caspase-1, and nuclear factor-κB and the phosphorylation of extracellular signal-regulated protein kinases, the c-Jun N-terminal kinase, and p38.

Dalargin, a potent δ-opioid receptor agonist, demonstrates efficacy in mitigating cell death induced by Gentamicin and exhibits nephroprotective effects against Gentamicin-induced kidney injury. Additionally, Dalargin possesses antiulcer activity [1] [2] [3].

Mulberroside A (Standard) is a reference standard for research and analysis in studies involving Mulberroside A. 1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of melanogenesis. 3. Mulberroside A has anti-inflammatory antiapoptotic effects. by decreasing the expressions of tumor necrosis factor-α (TNF-α), interleukin (IL)-1β, and IL-6 and inhibiting the activation of NALP3, caspase-1, and nuclear factor-κB and the phosphorylation of extracellular signal-regulated protein kinases, the c-Jun N-terminal kinase, and p38.

Lactiflorin is a monoterpene glycoside from paeony root. Lactiflorin possesses nephroprotective effect.

Trans-Psoralenoside exhibits hepatoprotective (liver-protective), nephroprotective (kidney-protective), antiulcer, and anticoagulant properties.