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(5)
By Target- E1/E2/E3 Enzyme
- NEDD8(3)
- Apoptosis(1)
- Serine Protease(1)
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Results for "
nedd8 activating enzyme (nae)
" in TargetMol Product Catalog- Inhibitors & Agonists6
Pevonedistat
MLN4924
T6332905579-51-3
Pevonedistat (MLN4924) is a potent and selective NEDD8 activating enzyme (NAE) inhibitor (IC50=4.7 nM) with therapeutic potential for myelodysplastic syndromes (MDS) and antitumor activity.
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NAE-IN-M22
NEDD8 inhibitor M22
T8816864420-54-2
NAE-IN-M22 (NEDD8 inhibitor M22) is a selective, potent and reversible inhibitor of NEDD8 activating enzyme (NAE). NAE-IN-M22 inhibits multiple cancer cell lines and induces apoptosis in A549 cells. NAE-IN-M22 also can inhibit tumor growth in vivo.
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TAS4464 hydrochloride
T130901848959-11-4
TAS4464 hydrochloride is a highly potent and selective NEDD8 activating enzyme (NAE) inhibitor(IC50 of 0.955 nM).
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ZM223
ZM-223
T134122031177-48-5
ZM223 is an inhibitor of NEDD8 activating enzyme (NAE).
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ZM223 hydrochloride (2031177-48-5 free base)
ZM223 hydrochloride
T13412L
ZM223 hydrochloride is an orally active, potent non-covalent inhibitor of NEDD8 activating enzyme (NAE), and with excellent anticancer activity.
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