ncx1

NCX1-IN-1 (Compound 6) is an inhibitor of the Na+ Ca2+ exchanger (NCX).

NCX1022 is a NO-releasing derivative of Hydrocortisone. It is the most widely used anti-inflammatory drug for the treatment of skin inflammation.

SN 6 (SN6) is a selective Na+ Ca2+ exchanger (NCX) inhibitor (IC50s of NCX1: 2.9 μM , NCX2: 16 μM ,NCX3: 8.6 μM)

12-O-deacetyl-phomoxanthone is a sodium-calcium exchanger NCX1 antiporter agonist with IC50 = 5.2µM for gastric cancer AGS cells.

YM-244769 dihydrochloride is an effective inhibitor of Na+ Ca2+ exchange 3 (NCX3) with an IC50 of 18 nM. YM-244769 dihydrochloride has efficient protective effects on neurons and kidneys.

Bepridil hydrochloride hydrate ((±)-Bepridil hydrochloride hydrate) is a long-acting, non-selective calcium channel (Ca+ channel) antagonist, an inhibitor of the Na+, K+ channel, and an inhibitor of cardiac Na+ Ca2+ exchange (NCX1).

pTH-Related Protein (1-40) (human, mouse, rat) enhances calcium absorption in rat intestinal cells by activating the PTHR1 receptor and the PKCα β signaling pathways. This compound also increases the expression of the parathyroid hormone 1 receptor (PTHR1) and four key proteins involved in transcellular calcium transport: potential vanillin member 6 (TRPV6), calcium-binding protein-D9K (CaBP-D9k), sodium-calcium exchanger 1 (NCX1), and plasma membrane calcium ATPase 1 (PMCA1) [1].