ncbzpheargamchydrochloride(65147220freebase)

N-CBZ-Phe-Arg-AMC hydrochloride (Z-Phe-Arg-Amc HCl) is a substrate for catS protease. CatS protease is an important member of the cysteine protease family and is a lysosomal protease. It is expressed in many inflammatory processes and autoimmune diseases and can be used to assess the activity of lysosomal proteases.

N-CBZ-Phe-Arg-AMC (Z-FR-AMC) is a substrate for serine proteases, including cathepsins, kallikrein, and plasmin. The substrate exhibits absorption/emission at 330/390 nm (weak fluorescence), while the end product (AMC) shows absorption/emission at 342/441 nm (strong fluorescence).

N-CBZ-Phe-Arg-AMC TFA (Z-FR-AMC TFA) is a fluorescent substrate for serine proteases, which releases free AMC upon protease cleavage. Its excitation/emission wavelengths are 380/460 nm, and it can be used to assess the activity of trypsin, plasmin, and cathepsin.