n-butanoyl-l-homoserine lactone

N-Butanoyl-L-homoserine lactone (C4-HSL) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It exhibits antibacterial activity and is employed in antibacterial biofilm[1].

N-Butyryl-L-Homoserine lactone-d5 is a deuterated version of N-Butanoyl-L-homoserine lactone. Serving as a cleavable ADC linker, N-Butanoyl-L-homoserine lactone (C4-HSL) is employed in the synthesis of antibody-drug conjugates (ADCs). This compound also exhibits antimicrobial activity, making it useful in combating bacterial biofilms. Additionally, N-Butanoyl-L-homoserine lactone aptamers are employed to inhibit quorum sensing and prevent the formation of Pseudomonas aeruginosa biofilms.