mucolytic

Bromhexine hydrochloride (Bisolvon) is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus.

Eprazinone dihydrochloride (NSC 317935) is a mucolytic with antitussive and mucolytic effect.

Acetylcysteine (NAC) is an N-acetyl derivative of cysteine, a ROS inhibitor and mucolytic agent. Acetylcysteine induces apoptosis, can be used to reduce mucus thickness, and has anti-influenza viral activity.

IQB-782 is a mucolytic agent with mucolytic expectorant activity.IQB-782 inhibits thrombin-activating fibrinolytic inhibitor (TAFI), protects rats from tobacco smoke-induced respiratory obstruction, reduces the viscosity of gastric mucin suspensions in vitro, and may be useful in studies of obstructive lung disease.IQB-782 has been shown to reduce the viscosity of gastric mucin suspensions in vitro.

Erdosteine (RV 144) is a homocysteine-derived thiol derivative with mucolytic and free radical scavenging properties. Erdosteine and its metabolites modulate mucus production and viscosity, by which facilitating mucociliary transport and improving expectoration. This agent also suppresses the chemical-induced cough reflex as well as protects lung tissues from damages caused by cigarette smoking mediated through free radicals scavenging.

Fexlamose is an interventional nebulization solution with mucolytic properties, intended for research in chronic obstructive pulmonary disease (COPD).

Carbocisteine is an orally effective mucolytic agent. It inhibits the phosphorylation of NF-κB p65 and ERK1/2, regulates the crosstalk between Nrf2/HO-1 and NF-κB, and inhibits apoptosis, making it applicable in chronic obstructive pulmonary disease (COPD) research.

S-Carboxymethyl-L-cysteine L-lysine monohydrate (Carbocisteine lysine) is a mucolytic agent with anti-inflammatory and antioxidant properties, utilized in the study of chronic obstructive pulmonary disease (COPD).

Bromhexine is an expectorant/mucolytic agent which can be used in the treatment of respiratory disorders associated with excessive mucus or viscid.

Cistinexine is an expectorant and mucolytic from cystine.

Acetylcysteine-15N is a version of Acetylcysteine (T0875) labeled with nitrogen-15 (\[^15N\]). Acetylcysteine (N-Acetylcysteine) functions as a mucolytic agent, effectively reducing mucus viscosity. As a reactive oxygen species (ROS) inhibitor, it serves as a cysteine precursor and prevents heme-induced ferroptosis by neutralizing toxic lipids produced via arachidonic acid-dependent 5-lipoxygenase activity. Additionally, Acetylcysteine (T0875) can induce apoptosis and exhibits antiviral activity against influenza. It represents the most stable form of cysteine for drug delivery and is utilized in studies of disulfidptosis.

Acetylcysteine-D3 is the deuterated form of Acetylcysteine. Acetylcysteine (T0875) (N-Acetylcysteine), a mucolytic agent, is utilized to decrease mucus viscosity. It functions as an ROS inhibitor and serves as a precursor to cysteine. By neutralizing the toxic lipids produced via arachidonic acid-dependent 5-lipoxygenase activity, it helps prevent ferroptosis induced by heme. Furthermore, Acetylcysteine (T0875) can trigger apoptosis and exhibits antiviral activity against influenza viruses. It represents the most stable form of cysteine for drug delivery, suitable for disulfidptosis research.

Bromhexine-D3 hydrochloride is a deuterated compound of Bromhexine Hydrochloride (T0828). Bromhexine hydrochloride has a CAS number of 611-75-6. Bromhexine hydrochloride is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus.

trans-Sobrerol (NRM-331) is a potent mucolytic agent. It exhibits anti-amnesic effects by enhancing hippocampal cholinergic signaling and possesses the ability to inhibit the synthesis of tau proteins and Aβ proteins. Additionally, trans-Sobrerol alleviates memory impairment induced by Scopolamine and is applicable in Alzheimer's disease research.

Levanase is a mucolytic enzyme from the Rhodotorula genus. It randomly hydrolyzes β-2,6 fructofuranosidic linkages in β-2,6 fructans that contain more than three fructose units.