mrs

MRS 1754 is a selective antagonist radioligand for the A2B adenosine receptor, exhibiting very low affinity for A1 and A3 receptors in both humans and rats.

MRS-3777 hemioxalate, a selective adenosine A3 receptor antagonist, reverses the anti-injury perception effects of its corresponding agonist and serves as a valuable tool for studying inflammatory pain.

MRS1845 is an ORAI1 inhibitor and calcium entry (SOCE) blocker that blocks VP-induced SOCE, OS, and Ca(2+) deposition.

MRS-1191 is an effective and selective A3 adenosine receptor antagonist (KB: 92 nM, a Ki: 31.4 nM for human A3 receptor and an IC50: 120 nM for CHO cells).

MRS 1523 can exert an antihyperalgesic effect through N-type Ca channel block and action potential inhibition in isolated rat dorsal root ganglion (DRG) neurons. MRS 1523 is an effective and selective adenosine A3 receptor antagonist Ki: 18.9 nM and 113 n

MRS-1706 has Ki values of 1.39, 112, 157, and 230 nM for human A2B, A2A, A1, and A3 receptors respectively. MRS-1706 is an effective and selective adenosine A2B receptor inverse agonist.

MRS1177 is an effective and selective antagonist of the human Adenosine A3 receptor (hA3AR) (Ki: 0.3 nM).

MRS1186 is an effective and selective antagonist of the human Adenosine A3 receptor (Ki: 7.66 nM).

MRS2698 is an effective and highly selective agonist of the P2Y2 receptor (EC50: 8 nM). MRS2698 also is >300-fold P2Y2-selective versus the P2Y4 and P2Y6 receptors.

MRS4608 is a novel and potent antagonist of the P2Y14 receptor.

MRS4654 is an innovative and potent antagonist of the P2Y14 receptor, featuring an IC50 of 15 nM.

MRS1220, a selective and potent antagonist for the human A3 adenosine receptor (hA3AR) with a dissociation constant (Ki) of 0.59 nM, exhibits therapeutic promise for central nervous system disease research. It effectively diminishes glioblastoma tumor size and inhibits blood vessel formation in vivo.

antagonist for the human adenosine A3 receptor

competitive antagonist at P2Y1 receptors

P2Y13 receptor antagonist

Selective, high affinity competitive antagonist of the P2Y1 receptor

Highly potent, selective P2Y1 receptor agonist

Highly potent and selective antagonist of the platelet P2Y1 receptor

P2Y14 receptor agonist

MRS 2693 trisodium salt is a P2Y6 agonist.

MRS 2768 tetrasodium salt is a P2Y2 agonist.

MRS2500 is a highly potent and selective platelet P2Y1 receptor antagonist.

MRS4458 is an effective inhibitor of the P2Y14 Receptor.

MRS4478 is an effective inhibitor of the P2Y14 Receptor.