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By Target- Apoptosis
- Dopamine Receptor(1)
- Estrogen Receptor/ERR(1)
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Results for "
mpp hydrochloride
" in TargetMol Product Catalog- Inhibitors & Agonists3
- Disease Modeling1
MPP hydrochloride
MPP hydrochloride (289726-02-9 Free base)
T21897L
MPP hydrochloride is a selective estrogen receptor (ERR) modulator.
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MPTP hydrochloride
MPTP-hydrochloride
T408123007-85-4
MPTP hydrochloride is a precursor of MPP+, a dopamine neurotoxin with blood-brain barrier permeability. MPTP hydrochloride is toxic to dopaminergic neurons, which can lead to Parkinson's disease, and is widely used in the construction of animal models of Parkinson's disease.
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RWJ52353 hydrochloride
T87348245744-13-2
RWJ-52353 hydrochloride is a potent oral agonist of the α2D adrenergic receptor (Ki: 1.5 nM) with potential analgesic properties. It exhibits pain-relief activity in abdominal tests on rats and mice and reduces agitation in mice during the hot plate and tail flick tests. Furthermore, RWJ-52353 hydrochloride modulates the organic cation transporter (OCT) subtypes by inhibiting rOCT1 and rOCT2 with IC50 values of 100 μM and 20 μM, respectively, and activating rOCT3, influencing the transport of [3H]-1-methyl-4-phenylpyridinium ([3H]MPP) in cells [1] [2].
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