Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • Histone Methyltransferase
    (4)
  • Apoptosis
    (1)
  • HDAC
    (1)
  • Others
    (5)
Filter
Search Result
Results for "

mll1-wdr5

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    10
    TargetMol | Inhibitors_Agonists
  • Recombinant Protein
    1
    TargetMol | Recombinant_Protein
WDR5-47
T676971422389-91-0
WDR5-47 is a potent small molecule to disturb the interaction of MLL1-WDR5 with IC50 value of 0.3μM.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Sale
WDR5-0102
T67947824960-50-1
WDR5-0102 is a compound that inhibits the WDR5-MLL1 interface (K dis = 7 μM, K d = 4 μM), selectively reducing MLL1 HMT activity without affecting the human H3K4 methyltransferase SETD7 or other HMTs, including G9a, EHMT1, SUV39H2, SETD8, PRMT3, and PRMT5.
  • Inquiry Price
6-8 weeks
Size
QTY
MM-102
MM102, HMTase Inhibitor IX
T63331417329-24-8
MM-102 (HMTase Inhibitor IX) is a potent inhibitor of WDR5 MLL interaction with IC50 of 2.4 nM and Ki of less than 1 nM in a WDR5 binding assay. MM-102 can also specifically inhibit cell growth and induce apoptosis in leukemia cells carrying MLL1 fusion protein.
  • Inquiry Price
4-6 weeks
Size
QTY
DD0-2363
T205395
DD0-2363 (Compound 32d) is a dual-target inhibitor of WDR5-MLL1 HDAC. It can suppress the proliferation of acute myeloid leukemia cells and induce apoptosis. With its antitumor properties, DD0-2363 is applicable for research on acute myeloid leukemia.
  • Inquiry Price
Size
QTY
DDO-2093
T397692250024-74-7
DDO-2093, a powerful inhibitor of the MLL1-WDR5 protein-protein interaction (IC50 = 8.6 nM; Kd = 11.6 nM), exhibits prominent antitumor effects. Notably, DDO-2093 selectively hampers the catalytic activity of the MLL complex.
  • Inquiry Price
Size
QTY
DC_M5_2
T68821713099-37-7
DC_M5_2 is a novel inhibitor of wdr5-mll1 interaction
  • Inquiry Price
6-8 weeks
Size
QTY
DDO-2093 dihydrochloride
T72239
DDO-2093 dihydrochloride, a potent inhibitor of MLL1-WDR5 protein-protein interactions (IC50=8.6 nM; Kd=11.6 nM), exhibits antitumor activity. It selectively inhibits the catalytic activity of the MLL complex.
  • Inquiry Price
6-8 weeks
Size
QTY
MM-401 TFA
T752581442106-11-7
MM-401 (TFA), an MLL1 H3K4 methyltransferase inhibitor, effectively impedes MLL1 activity (IC 50 = 0.32 µM) by preventing MLL1-WDR5 interaction. It can induce cell cycle arrest, apoptosis, and differentiation, offering potential for MLL leukemia research [1].
  • Inquiry Price
7-10 days
Size
QTY
DDO-2213
T825982378768-36-4
DDO-2213 is a potent, orally active inhibitor of the WDR5-MLL1 interaction, demonstrating an IC50 of 29 nM and a Kd of 72.9 nM against WDR5. It selectively inhibits MLL (mixed lineage leukemia) histone methyltransferase activity, and suppresses the proliferation of cells harboring MLL translocations, positioning it as a valuable tool for MLL fusion leukemia research [1].
  • Inquiry Price
8-10 weeks
Size
QTY
MM-102 TFA
HMTase Inhibitor IX TFA
T87681883545-52-5
MM-102 TFA (HMTase Inhibitor IX TFA) is a potent WDR5 MLL interaction inhibitor with an IC50 of 2.4 nM. This compound prevents the interaction between mixed lineage leukemia 1 (MLL1) and WD Trp-Asp repeat domain 5 (WDR5), inhibiting MLL1 H3K4 histone methyltransferase (HMT) activity and down-regulating H3K4me3, which facilitates the epigenetic reprogramming of porcine somatic cell nuclear transfer embryos.
  • Inquiry Price
Size
QTY