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(2)
By Target- GPX
- Ferroptosis(1)
- Glutathione Peroxidase(1)
- Ras(1)
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Results for "
ml210
" in TargetMol Product Catalog- Inhibitors & Agonists2
ML-210
CID 49766530
T83751360705-96-9
ML-210 (CID 49766530) is a glutathione peroxidase 4 (GPX4) inhibitor (EC50=30 nM) that is covalent and selective. ML-210 has antitumor activity and induces ferroptosis.
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JKE-1674
T373142421119-60-8
JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210, which is converted to butyronitrile oxide JKE-1777. JKE-1674 kills LOX-IMVI cells in the same manner as ML-210 and is completely rescued by ferroptosis inhibitors.
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