ml 190

κ opioid receptor (KOP) antagonist

NC190 is an inhibitor of topoisomerase II that inhibited the growth of FM3A cells in clinical trials. NC-190 strongly inhibited the growth of FM3A cells when cultured with NC-190 for 48 h (IC50: 0.019 μg/ml). NC-190 potently suppressed DNA synthesis with

L-Ascorbic acid 6-stearate, a compound derived from L-ascorbic acid and stearic acid identified in K. coccinea, exhibits antioxidant and anticancer properties. It effectively scavenges DPPH radicals in cell-free assays (IC50 = 3.31 µg/ml). Additionally, lipid nanoparticles (LNPs) containing L-ascorbic acid 6-stearate have been shown to trigger apoptosis in HL-60 promyeloblasts at a concentration of 190 µM. This compound is also incorporated into cosmetic and personal care product formulations due to its beneficial effects.