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mk8776

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
sch900776
MK-8776, MK 8776
T2517891494-63-6
SCH900776 (MK-8776) is an agent targeting cell cycle checkpoint kinase 1 (Chk1) with potential radiosensitization and chemosensitization activities.
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SCH900776 (S-isomer)
SCH900776 S-isomer, MK-8776 S-isomer
T3700891494-64-7
SCH900776 S-isomer (MK-8776 S-isomer) is an effective, specific and orally bioavailable inhibitor of checkpoint kinase Chk1 (IC50: 3 nM). It also inhibitors Chk2 (IC50: 1500 nM) and cyclin-dependent kinase CDK2 (IC50: 160 nM).
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