metap-2

M8891 is an orally active, reversible, and brain-penetrant Methionine Aminopeptidase-2 (MetAP-2) inhibitor (IC50: 54 nM; Ki: 4.33 nM). It inhibits the growth of primary endothelial cells and tumor cells, demonstrating both antiangiogenic and antitumoral activity.

TP-004 is a potent, reversible inhibitor of methionine aminopeptidase 2 (MetAP2) with an IC50 of 6 nM.

Fumagillin (Amebacilin) is a selective and potent irreversible inhibitor of Methionine aminopeptidase 2 (MetAP2), used as an antibiotic to treat microsporidiosis.

MetAP2-IN-1 is a selective inhibitor of MetAP2, a target involved in angiogenesis-related conditions, suitable for research applications [1].

SB-587094 is a reversible inhibitor of methionine aminopeptidase-2 (MetAP-2).

CKD-731 is an analogue of Fumagillin. It inhibits the proliferation of bovine pulmonary artery endothelial cells, lymphoma EL-4 cells, and mouse leukemia P388D1 cells. CKD-731 functions by inhibiting MetAP-2 activity and blocking angiogenesis. It is applicable in studies related to angiogenesis-associated cancers.

JNJ-4929821 is a potent, reversible methionine aminopeptidase-2 (MetAP-2) inhibitor with IC50 of 8 nM.

LAF-153 is a reversible Methionine Aminopeptidase‑2 (MetAP-2) Inhibitor.