mark-4 inhibitor 1

MARK4 inhibitor 1 inhibits cancer cell proliferation, metastasis and induces apoptosis. MARK4 inhibitor 1 is a potent microtubule affinity-regulating kinase 4 (MARK4) inhibitor, with an IC50 of 1.54 μM.

MARK-IN-4 is a potent microtubule affinity regulating kinase (MARK) inhibitor with an IC50 value of 1 nM. In the pathology of Alzheimer's disease, MARK kinases are responsible for the phosphorylation of Tau protein; hyperphosphorylation of Tau leads to the formation of neurofibrillary tangles and the destabilization of microtubule structures. By potently inhibiting MARK activity, MARK-IN-4 serves as a crucial pharmacological tool for researching the arrest of neurodegenerative disease progression.