lopinavir

Lopinavir (ABT-378) is a peptidomimetic HIV protease inhibitor effective against HIV protease with the Val 82 mutation. It is less affected by serum protein binding compared to the structurally related drug ritonavir.

Lopinavir M-3/M-4 is a Lopinavir secondary metabolite.

Lopinavir Metabolite M-1, an active metabolite of Lopinavir, effectively inhibits the HIV protease enzyme with a Ki value of 0.7 pM, demonstrating notable antiviral properties in [in vitro] studies.

Lopinavir-d8 is a deuterated compound of Lopinavir. Lopinavir has a CAS number of 192725-17-0. Lopinavir is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation. Lopinavir is less affected by binding to serum proteins than the structurally-related drug ritonavir.

KNI-1657 is a potent and selective HIV-1 protease inhibitor (Anti-HIV-1 pNL4-3, EC50: 3 nM). KNI-1657 is a highly potent HIV-1 Protease Inhibitor against Lopinavir.