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lkynurenine

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  • Inhibitors & Agonists
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L-Kynurenine
(S)-Kynurenine
T49282922-83-0
L-Kynurenine ((S)-Kynurenine) is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has been shown to inhibit allogeneic T-cell proliferation and to increase malignant U87 glioma cell invasion into a collagen matrix.
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L-Kynurenine-d4-1
TMIJ-0518194546-33-3
L-Kynurenine-d4-1 is a deuterated compound of L-Kynurenine. L-Kynurenine has a CAS number of 2922-83-0. L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has been shown to inhibit allogeneic T-cell proliferation and to increase malignant U87 glioma cell invasion into a collagen matrix.
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20 days
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L-Kynurenine-d4
TMID-00712672568-86-2
L-Kynurenine-d4 is a deuterated compound of L-Kynurenine. L-Kynurenine has a CAS number of 2922-83-0. L-Kynurenine is a key intermediate in the breakdown pathway of tryptophan. L-Kynurenine is a substrate of kynureninase, KMO, and KAT associated with the suppression of antitumor immune responses. It has been shown to inhibit allogeneic T-cell proliferation and to increase malignant U87 glioma cell invasion into a collagen matrix.
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20 days
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TargetMol
L-Kynurenine sulfate
T7243016055-80-4
L-Kynurenine sulfate, an aryl hydrocarbon receptor (AHR) agonist, activates AHR-driven polarization of naive T cells towards the anti-inflammatory [Treg] phenotype.
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6-8 weeks
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Kynurenine sulfate monohydrate
L-Kynurenine sulfate monohydrate
T3011L5965-60-6
Kynurenine sulfate monohydrate is a precursor of kynurenic acid which is the only recognized endogenous excitatory amino acid receptor antagonist agent in the central nervous system. L-Kyn is known to be a pigment generating component in animals. In mamma
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6-8 weeks
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TargetMol
D-Kynurenine
ZINC901103, (R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid
T1093813441-51-5
D-Kynurenine (ZINC901103) is a metabolite of D-tryptophan and an agonist of GPR109B. D-Kynurenine activates AhR and promotes the conversion of the epithelium to mesenchyme. D-Kynurenine serves as a substrate in the fluorescence analysis of D-amino acid oxidase.
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4-6 weeks
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TargetMol
2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid
Kynurenine, Kynurenin, Dl-Kynurenine, 3-Anthraniloylalanine
T3011343-65-7
2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid (3-Anthraniloylalanine) is a ketone and amino acid derivative with diverse biological functions, including vasodilatory, immunoregulatory, and neuromodulatory activities. It is a precursor for niacin and its aberrant production is linked to neurological disease-related cognitive deficits and depressive symptoms. This compound is overexpressed in certain cancer cell types and could potentially serve as a biomarker to assess cancer risk.
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