lincosamide

Clindamycin (Sobelin) dissociates peptidyl-tRNA from the bacterial ribosome, thereby disrupting bacterial protein synthesis. Clindamycin is a semisynthetic broad-spectrum antibiotic produced by chemical modification of the parent compound lincomycin.

Clindamycin Phosphate is the phosphate salt form of clindamycin, a semi-synthetic, chlorinated broad-spectrum antibiotic produced by chemical modification of lincomycin. Clindamycin phosphate (Clindamycin 2-dihydrogen phosphate) is used in topical preparations.

Lincomycin hydrochloride (U10149A) is a lincosamide antibiotic identified in S.lincolnensis with activity against gram-positive cocci and anaerobic bacteria.

Quinupristin is a member of the macrolide-lincosamide-streptogramin class of antibiotics. Quinupristin blocks peptide bond synthesis to prevent the extension of polypeptide chains and promote the detachment of incomplete protein chains in the bacterial ribosomal subunits[1] [2].

Lincosamine is a lincosamide antibiotic produced by Streptomyces lincolnensis.

Lincomycin (U-10149) is a lincosamide antibiotic from Streptomyces that is effective against most susceptible gram-positive and cell wall-less bacteria and is generally used in patients for whom penicillin is not available.

Clindamycin palmitate hydrochloride (Clindamycin palmitate HCl) is a water soluble hydrochloride salt of the ester of clindamycin and palmitic acid and a lincosamide antibiotic.

Clindamycin phosphate hydrochloride (Clindamycin 2-phosphate), a broad-spectrum bacteriostatic lincosamide antibiotic, serves as a prodrug of Clindamycin. It lacks antimicrobial activity in vitro; however, through phosphatase ester hydrolysis, it is rapidly converted to the active form, Clindamycin, in vivo. This compound is utilized in the research of acne and bacterial vaginosis [1] [2] [3].

Lincomycin-B is a lincosamide antibiotic isolated from the actinomycete Streptomyces lincolnensis.