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By Target- Histone Methyltransferase
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Results for "
karpas-422
" in TargetMol Product Catalog- Inhibitors & Agonists3
PF-06726304
T12428L1616287-82-1
PF-06726304 shows robust antitumor growth activity. PF-06726304 is an effective and selective EZH2 inhibitor. PF-06726304 inhibits wild-type and Y641N mutant EZH2 (Kis: 0.7 and 3.0 nM, respectively).
- $33
Size
QTY
Antitumor agent-23
T398892355185-12-3
Antitumor agent-23 exhibits potent antitumoral activity, as demonstrated by its GI50 values of 38, 48, 5, 27, 80, and 28 nM against the lymphoma cell lines GRANTA-519, KARPAS-422, KARPAS-299, RAMOS, DAUDI, and RAJI respectively.
- $1,520
Size
QTY
EZH2-IN-17
T863942489672-09-3
EZH2-IN-17 (compound 28), an orally active and potent inhibitor of EZH2, demonstrates an IC50 value of 0.95 nM. It shows significant anti-proliferation effects on various lymphoma cell lines including WSU-DLCL2, Pfeiffer, and Karpas-422, with IC50 values of 2.36 nM, 1.73 nM, and 1.82 nM, respectively [1].
- $1,670
Size
QTY
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