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itd1

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
ITD-1
T22731099644-42-4
ITD-1 is a potent and highly selective TGFβ pathway inhibitor.
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(+)-ITD-1
T2016721409968-46-2
(+)-ITD-1 is an inhibitor of TGF-β, effectively inhibiting TGF-β2 with an IC50 of 0.46 μM. It promotes the degradation of the TGF-β type II receptor (TGFBR2) and the differentiation of cardiomyocytes. Additionally, it suppresses the formation of the mesoderm during the early differentiation of mouse embryonic stem cells (mESCs).
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10-14 weeks
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