insecticides

Sucrose octaacetate is an acetylated derivative of sucrose used as a food additive, binder, and plasticizer. It is also incorporated in many pesticides, insecticides, and other toxic products as a deterrent to accidental poisoning.

Azadirachtin has antifungal activity, used as an insecticide.

Tolfenpyrad is an effective insecticide[1], used against pests that are resistant to existing insecticides such as organophosphates and carbamates.[2]

3-Phenoxybenzaldehyde cyanohydrin (2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile) is an intermediate of pyrethroid insecticides such as fenpermethrin.

Spirostan-3-ol (Sarsaponin) is a stereoisomer of Sarsasapogenin (S142505), a steroid glycoside isolated from plant materials. A saponin with with potential anti-tumor activity via apoptosis.

2,4-Dimethylthiazole can be used as a raw material for insecticides and fungicides to control crop pests and diseases.

Formothion is a chemical compound. It is used in acaricides and insecticides.

V-ATPase-IN-1 (Compound 3b-03) is an inhibitor of Vacuolar-type H+-ATPases (V-ATPase), exhibiting an inhibition constant (IC50) of 194.80 μM and effectively targeting the V-ATPase subunit A with a dissociation constant (Kd) of 0.803 μM. This compound demonstrates insecticidal activity against M. separata (LC50 = 2.64 mM), aiding in the development of chemical insecticides.

ETNK-IN-1 (Compound 7) is an ethanolamine kinase (ETNK) inhibitor with an IC50 value of ≥ 5 μM, and it is applicable in research for developing insecticides.

Insecticidal agent 21 (Compound 6) is an insecticide targeting Culex pipiens larvae with an LC50 of 0.4 μg/mL. It achieves multi-target neurotoxicity by inhibiting acetylcholinesterase (AChE) and simultaneously targeting other neural receptors, including nicotinic acetylcholine receptors (nAChR), voltage-gated sodium channels (VGSC), and γ-aminobutyric acid receptors (GABAAR). Insecticidal agent 21 shows potent insecticidal activity and can be utilized in the development of new insecticides to combat mosquito resistance to conventional agents.

Pyridalyl belongs to the dihalopropenyloxybenzene class of insecticides. It is effective on Thysanoptera and Lepidoptera pests.

Cyphenothrin, a synthetic pyrethroid insecticide, is effective against cockroaches that have developed resistance to carbamate and organophosphorous insecticides.

Empenthrin, a synthetic pyrethroid used in insecticides, is active against broad spectrum of flying insects including moths and other pests damaging textile.

Spinosyn A is a polyketide-derived macrolide produced by Saccharopolyspora spinosa and is an active ingredient in several commercial insecticides.

Aldrin-transdiol is a metabolite of dieldrin. Aldrin-transdiol may be used in insecticides.

Eprinomectin B1b, a minor component of the avermectin family, is used as an insecticide and anthelmintic.

(4′-Hydroxy)phenoxybenzoic acid is a pyrethroid insecticide metabolite.1,2 1.Akhtar, M.H., Mahadevan, S., and Russell, F.Cleavage of 3-phenoxybenzoic acid by chicken microsomal preparationsJ. Environ. Sci. Health B.28(5)527-543(1993) 2.Maloney, S.E., Maule, A., and Smith, A.R.Microbial transformation of the pyrethroid insecticides: Permethrin, deltamethrin, fastac, fenvalerate, and fluvalinateAppl. Environ. Microbiol.54(11)2874-2876(1988)

OfChi-h-IN-2 (compound TQ19) is a potent OfChi-h inhibitor with a K_i of 0.33 μM, significantly impairing the growth and development of Ostrinia nubilalis larvae, and is relevant for agricultural insecticide research [1].

Eprinomectin B1a, composing over 90% of the antiparasitic agent eprinomectin, is a primary component alongside eprinomectin B1b, which constitutes less than 10%. This compound is part of the avermectin family, used as insecticides and anthelmintics.

Phytoalexine (Compound 8) is a plant antitoxin found in mustard, exhibiting antifungal properties against fungi such as Phoma lingam and Phoma wasabiae. It inhibits fungal spore germination and hyphal growth, showing promise for research into insecticides targeting plant fungal diseases.

8-Aminoquinoline is a molecular block that is a nitrogen-containing heterocyclic skeleton common in many natural products, functional materials and useful drugs. It has antibacterial, antiviral and anti-tumor activities, and can be used as an active ingredient in insecticides and herbicides.