insecticides

Sucrose octaacetate is an acetylated derivative of sucrose used as a food additive, binder, and plasticizer. It is also incorporated in many pesticides, insecticides, and other toxic products as a deterrent to accidental poisoning.

Azadirachtin has antifungal activity, used as an insecticide.

3-Methylthiophene is mainly used in pharmaceutical synthesis and serves as an intermediate for various drugs. 3-Methylthiophene can also be used as a raw material for the synthesis of pesticides such as insecticides. 3-Methylthiophene can also be used to prepare various conductive polymer materials.

Tolfenpyrad is an effective insecticide[1], used against pests that are resistant to existing insecticides such as organophosphates and carbamates.[2]

3-Phenoxybenzaldehyde cyanohydrin (2-Hydroxy-2-(3-phenoxyphenyl)acetonitrile) is an intermediate of pyrethroid insecticides such as fenpermethrin.

Spirostan-3-ol (Sarsaponin) is a stereoisomer of Sarsasapogenin (S142505), a steroid glycoside isolated from plant materials. A saponin with with potential anti-tumor activity via apoptosis.

2,4-Dimethylthiazole can be used as a raw material for insecticides and fungicides to control crop pests and diseases.

Furan, as an intermediate in organic synthesis, is a core raw material for the preparation of various chemicals. For example, it is used to synthesize derivatives such as furfural and furoic acid. These derivatives are further applied in the pharmaceutical field (e.g., in the synthesis of certain antibiotics and antiparasitic drugs) and the pesticide field (as intermediates for some insecticides and fungicides). It can also be used to synthesize resins, rubber additives, fragrances and so on. In addition, derivatives of furan (such as tetrahydrofuran) are commonly used organic solvents. However, due to its toxicity and volatility, furan itself is rarely directly used as a solvent.

Formothion is a chemical compound. It is used in acaricides and insecticides.

V-ATPase-IN-1 (Compound 3b-03) is an inhibitor of Vacuolar-type H+-ATPases (V-ATPase), exhibiting an inhibition constant (IC50) of 194.80 μM and effectively targeting the V-ATPase subunit A with a dissociation constant (Kd) of 0.803 μM. This compound demonstrates insecticidal activity against M. separata (LC50 = 2.64 mM), aiding in the development of chemical insecticides.

ETNK-IN-1 (Compound 7) is an ethanolamine kinase (ETNK) inhibitor with an IC50 value of ≥ 5 μM, and it is applicable in research for developing insecticides.

Insecticidal agent 21 (Compound 6) is an insecticide targeting Culex pipiens larvae with an LC50 of 0.4 μg/mL. It achieves multi-target neurotoxicity by inhibiting acetylcholinesterase (AChE) and simultaneously targeting other neural receptors, including nicotinic acetylcholine receptors (nAChR), voltage-gated sodium channels (VGSC), and γ-aminobutyric acid receptors (GABAAR). Insecticidal agent 21 shows potent insecticidal activity and can be utilized in the development of new insecticides to combat mosquito resistance to conventional agents.

Pyridalyl belongs to the dihalopropenyloxybenzene class of insecticides. It is effective on Thysanoptera and Lepidoptera pests.

Cyphenothrin, a synthetic pyrethroid insecticide, is effective against cockroaches that have developed resistance to carbamate and organophosphorous insecticides.

Empenthrin, a synthetic pyrethroid used in insecticides, is active against broad spectrum of flying insects including moths and other pests damaging textile.

Thiotraniliprole (HY366) is a chemical belonging to the class of anthranilic diamide insecticides, designed for synthesizing pest control formulations. It shows potential applications in combating pests from the orders Lepidoptera and Coleoptera, as well as in the prevention of ants and termites.

Spinetoram J belongs to the macrolide class of insecticides. Spinetoram J acts on nicotinic acetylcholine receptors (nAChR) and GABA receptors in the insect nervous system, disrupting nerve conduction and leading to insect paralysis and death. Spinetoram J is typically one of the active components in spinetoram mixtures and exhibits high potency in agricultural pest control research.

Spinosyn A is a polyketide-derived macrolide produced by Saccharopolyspora spinosa and is an active ingredient in several commercial insecticides.

Aldrin-transdiol is a metabolite of dieldrin. Aldrin-transdiol may be used in insecticides.

Eprinomectin B1b, a minor component of the avermectin family, is used as an insecticide and anthelmintic.

(4′-Hydroxy)phenoxybenzoic acid is a pyrethroid insecticide metabolite.1,2 1.Akhtar, M.H., Mahadevan, S., and Russell, F.Cleavage of 3-phenoxybenzoic acid by chicken microsomal preparationsJ. Environ. Sci. Health B.28(5)527-543(1993) 2.Maloney, S.E., Maule, A., and Smith, A.R.Microbial transformation of the pyrethroid insecticides: Permethrin, deltamethrin, fastac, fenvalerate, and fluvalinateAppl. Environ. Microbiol.54(11)2874-2876(1988)

OfChi-h-IN-2 (compound TQ19) is a potent OfChi-h inhibitor with a K_i of 0.33 μM, significantly impairing the growth and development of Ostrinia nubilalis larvae, and is relevant for agricultural insecticide research [1].

Eprinomectin B1a, composing over 90% of the antiparasitic agent eprinomectin, is a primary component alongside eprinomectin B1b, which constitutes less than 10%. This compound is part of the avermectin family, used as insecticides and anthelmintics.

1,4-Dichlorobenzene-13C6 is the 13C-labeled version of 1,4-Dichlorobenzene. This compound serves as an intermediate in the production of pigments, insecticides, and disinfectants. Additionally, 1,4-Dichlorobenzene is used as a moth repellent.