il 11

IL-11 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 19.2 kDa and the accession number is A3KPB8.

IL-11 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 19.1 kDa and the accession number is AAH12506.1.

Interleukin 11 (IL-11) is a member of a family of human growth factors that includes human growth hormone, granulocyte colony-stimulating factor, and other growth factors. IL-11 is a thrombopoietic growth factor that directly stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. It also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2, It activates a signaling cascade that promotes cell proliferation. The signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.

Expression system: HEK293 Cells
Length: 22-199, Full Length of Mature Protein
Activity: SPR

Expression system: P. pastoris (Yeast)
Length: 22-199, Full Length of Mature Protein
Activity: Not Tested

IL-11 Protein, Rat, Recombinant (hFc) is expressed in Mammalian cell. The accession number is Q99MF5.

IL-11 Protein, Human, Recombinant (CHO) is expressed in CHO Cells. The accession number is P20809-1.

Expression system: HEK293 Cells
Length: 22-199, Full Length of Mature Protein
Activity: Not Tested

IL-11 Protein, Mouse, Recombinant (HEK293) is expressed in HEK293 Cells. The accession number is P47873.

IL-11 Protein, Human, Recombinant (hFc) is expressed in CHO Cells. The accession number is P20809-1.

Expression system: HEK293 Cells
Length: 22-199, Full Length of Mature Protein
Activity: ELISA、SPR

Expression system: E. coli
Length: 22-199, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 22-199, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 30-162, Partial
Activity: Cell Activity

gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic factor, and cardiotrophin-1. These cytokines exhibit pleiotropic biological activities in, for instance, immune, hematopoietic, and neural systems, and function in a redundant manner owing to the shared usage of gp130. gp130 IL6ST Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 68.94 kDa and the accession number is P40189-1.

Expression system: E. coli
Length: 25-112, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 26-120, Full Length of Mature Protein
Activity: Cell Activity

Expression system: E. coli
Length: 18-146, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 25-112, Full Length of Mature Protein
Activity: Cell Activity

Expression system: E. coli
Length: 32-162, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 113-271, Full Length of Mature Protein
Activity: Not Tested

Expression system: E. coli
Length: 109-266, Partial
Activity: ELISA

Interleukin-33 (IL-33) belongs to the IL-1 superfamily. IL33 is highly expressed in endothelial venules found in tonsils, Peyer patches and mesenteric lymph nodes, but almost undetectable in placenta. IL33 induces the production of T helper-2 (Th2)-associated cytokines. IL-33 is a cytokine that mediates its biological effects by binding to and signals through IL1RL1 ST2 and IL-1 Receptor Accessory Protein (IL1RAP), activating intracellular molecules in the NF-κB and MAP kinase signaling pathways that drive production of type 2 cytokines from polarized Th2 cells.

gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic factor, and cardiotrophin-1. These cytokines exhibit pleiotropic biological activities in, for instance, immune, hematopoietic, and neural systems, and function in a redundant manner owing to the shared usage of gp130. gp130 IL6ST Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.09 kDa and the accession number is F7FXB6.