hydrochlorothiazide

Hydrochlorothiazide (HCTZ) is a Thiazide Diuretic. The physiologic effect of hydrochlorothiazide is by means of Increased Diuresis.

Moexipril hydrochloride (Moexipril HCl) is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment of hypertension and congestive heart failure.

5-chloro Hydrochlorothiazide is a derivative of hydrochlorothiazide, which is a diuretic and antihypertensive agent that increases renal excretion of sodium, potassium, chloride, and bicarbonate ions by inhibiting tubular reabsorptive mechanisms.

Hydrochlorothiazide impurity C is a potential impurity found in commercial hydrochlorothiazide preparations. [1] Hydrochlorothiazide is a thiazide diuretic that inhibits the apical membrane sodium chloride cotransporter in the distal and collecting duct nephron segments.[2][3][4]

Hydrochlorothiazide-[13C6] (Standard) is a reference standard of Hydrochlorothiazide-[13C6] intended for quantitative analysis, quality control, and related biochemical research applications.

4-Amino-6-chlorobenzene-1,3-disulfonamide (Standard) is the standard substance of 4-Amino-6-chlorobenzene-1,3-disulfonamide, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 4-Amino-6-chlorobenzene-1,3-disulfonamide is a useful organic compound for research related to life sciences. The catalog number is T65709 and the CAS number is 121-30-2.

Hydrochlorothiazid-D2 (Standard) is a reference standard of Hydrochlorothiazid-D2 intended for quantitative analysis, quality control, and related biochemical research applications. Hydrochlorothiazid-d2 is a deuterated compound of Hydrochlorothiazid. Hydrochlorothiazid has a CAS number of 58-93-5. Hydrochlorothiazide is a Thiazide Diuretic. The physiologic effect of hydrochlorothiazide is by means of Increased Diuresis.

Benzylhydrochlorothiazide is an orally active thiazide diuretic that acts on the distal renal tubule to inhibit sodium chloride reabsorption, thereby increasing urine output and reducing body fluid volume. It possesses phototoxicity and potential skin reaction risks, causing cell death under UVA exposure. Benzylhydrochlorothiazide is useful for research on hypertension and edema.

Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazide appears to block the active reabsorption of chloride and possibly sodium in the ascending loop of Henle, altering electrolyte transfer in the proximal tubule.

Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.

Bendroflumethiazide (Naturetin) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)

Benazepril is an orally active ACE (angiotensin-converting enzyme) inhibitor commonly used to treat hypertension, heart failure, diabetic nephropathy, and other conditions. Benazepril is also studied in cardiovascular and renal physiology research systems to investigate angiotensin-converting enzyme inhibition, blood pressure regulation mechanisms, and renal hemodynamic responses in mammalian models. Benazepril is further applied in pharmacological research evaluating combination formulations such as benazepril/hydrochlorothiazide and benazepril/amlodipine in antihypertensive pathway modulation studies.

Pyrazinoylguanidine (PZG) is an analogue of the potassium-sparing diuretic amiloride. It can reduce systolic and diastolic blood pressure in patients with primary hypertension and has a slight effect on reducing heart rate without altering serum concentrations of electrolytes such as sodium, potassium, or chloride. Pyrazinoylguanidine also alleviates hyperglycemia and hyperinsulinemia in type 2 diabetes patients, lowers triglycerides, cholesterol, and free fatty acids, and can reverse the hyperglycemia and hyperlipidemia induced by thiazide diuretics like hydrochlorothiazide. Additionally, it inhibits renal tubular reabsorption of urea, enhancing urea clearance and excretion, thus reducing serum urea concentration and its toxic accumulation.

Fimasartan (BR-A-657) is a non-peptide angiotensin II receptor antagonist (ARB) used for the treatment of hypertension and heart failure. Concurrent administration of fimasartan with diuretic hydrochlorothiazide has shown to be safe in clinical trials.

Buthiazide (Butizide) is a diuretic compound commonly used in cardiovascular and renal research, particularly in studies focused on hypertension and fluid balance regulation, where Buthiazide was employed to investigate electrolyte transport, renal function, and blood pressure control mechanisms in both experimental and translational pharmacology settings.

4-Amino-6-chloro-1,3-benzenedisulfonamide is a carbonic anhydrase inhibitor.1 Formulations containing this compound are diuretics.2 4-Amino-6-chloro-1,3-benzenedisulfonamide is detected as a hydrolysis product of chlorothiazide in the urine.2 Diuretics, including chlorothiazide, have been abused as performance-enhancing drugs and masking agents in sports doping.3References1. Nishimori, I., Vullo, D., Minakuchi, T., et al. Carbonic anhydrase inhibitors: Cloning and sulfonamide inhibition studies of a carboxyterminal truncated α-carbonic anhydrase from Helicobacter pylori. Bioorg. Med. Chem. Lett. 16(8), 2182-2188 (2006).2. Deventer, K., Pozo, O.J., Van Eenoo, P., et al. Detection of urinary markers for thiazide diuretics after oral administration of hydrochlorothiazide and altizide-relevance to doping control analysis. J. Chromatogr. A 1216(12), 2466-2473 (2009).3. Cadwallader, A.B., de la Torre, X., Tieri, A., et al. The abuse of diuretics as performance-enhancing drugs and masking agents in sport doping: Pharmacology, toxicology and analysis. Br. J. Pharmacol. 161(1), 1-16 (2010). 4-Amino-6-chloro-1,3-benzenedisulfonamide is a carbonic anhydrase inhibitor.1 Formulations containing this compound are diuretics.2 4-Amino-6-chloro-1,3-benzenedisulfonamide is detected as a hydrolysis product of chlorothiazide in the urine.2 Diuretics, including chlorothiazide, have been abused as performance-enhancing drugs and masking agents in sports doping.3 References1. Nishimori, I., Vullo, D., Minakuchi, T., et al. Carbonic anhydrase inhibitors: Cloning and sulfonamide inhibition studies of a carboxyterminal truncated α-carbonic anhydrase from Helicobacter pylori. Bioorg. Med. Chem. Lett. 16(8), 2182-2188 (2006).2. Deventer, K., Pozo, O.J., Van Eenoo, P., et al. Detection of urinary markers for thiazide diuretics after oral administration of hydrochlorothiazide and altizide-relevance to doping control analysis. J. Chromatogr. A 1216(12), 2466-2473 (2009).3. Cadwallader, A.B., de la Torre, X., Tieri, A., et al. The abuse of diuretics as performance-enhancing drugs and masking agents in sport doping: Pharmacology, toxicology and analysis. Br. J. Pharmacol. 161(1), 1-16 (2010).

rac Bendroflumethiazide-D5 is a deuterated compound of rac Bendroflumethiazide. rac Bendroflumethiazide (T1204) has a CAS number of 73-48-3. A thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE. It has been used in the treatment of familial hyperkalemia, hypertension, edema, and urinary tract disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p810)

Hydrochlorothiazid-D2 is a deuterated compound of Hydrochlorothiazid. Hydrochlorothiazid (T1449) has a CAS number of 58-93-5. Hydrochlorothiazide is a Thiazide Diuretic. The physiologic effect of hydrochlorothiazide is by means of Increased Diuresis.

Chlorothiazide (Standard) is the standard substance of Chlorothiazide, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Chlorothiazide (Diuril) is a thiazide diuretic with actions and uses similar to those of HYDROCHLOROTHIAZIDE.

Trichlormethiazide (Standard) is the standard substance of Trichlormethiazide, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazide appears to block the active reabsorption of chloride and possibly sodium in the ascending loop of Henle, altering electrolyte transfer in the proximal tubule.