homocarnosine acetate

Homocarnosine acetate is a dipeptide unique to brain consisting of γ-aminobutyric acid (GABA) and histidine. Homocarnosine acetate has antioxidant and anti-inflammatory actions, prevention of DNA damage, and inhibition of advanced glycation end-product formation

Homocarnosine TFA, a unique dipeptide of γ-aminobutyric acid (GABA) and histidine found in the brain, acts as an inhibitory neuromodulator synthesized from GABA within neurons. It exhibits anticonvulsant effects [1], and possesses antioxidant and anti-inflammatory properties, prevents DNA damage, and inhibits the formation of advanced glycation end-products [2].

Homocarnosine is a brain-specific dipeptide composed of γ-aminobutyric acid (GABA) and histidine. As an inhibitory neurotransmitter, homocarnosine is synthesized from GABA within neurons and exerts anticonvulsant effects by enhancing GABA receptor signaling pathways. Homocarnosine also possesses antioxidant and anti-inflammatory properties; it scavenges peroxyl radicals, chelates transition metal ions such as copper, prevents oxidative damage to DNA, and inhibits the formation of advanced glycation end products (AGEs).